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    Arl13a ARF like GTPase 13A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 501617, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Arl13aprovided by RGD
    Official Full Name
    ARF like GTPase 13Aprovided by RGD
    Primary source
    RGD:1562947
    See related
    EnsemblRapid:ENSRNOG00000055454 AllianceGenome:RGD:1562947
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in non-motile cilium assembly and receptor localization to non-motile cilium. Predicted to be active in ciliary membrane and non-motile cilium. Orthologous to human ARL13A (ADP ribosylation factor like GTPase 13A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 34.6), Kidney (RPKM 20.0) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Arl13a in Genome Data Viewer
    Location:
    Xq32
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (101673637..101699986)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (97380370..97406704)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (105010943..105039720)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene cleavage stimulation factor subunit 2 Neighboring gene 60S ribosomal protein L36a-like Neighboring gene NADPH oxidase 1 Neighboring gene XK related, X-linked Neighboring gene tRNA methyltransferase 2 homolog B Neighboring gene transmembrane protein 35A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in non-motile cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in receptor localization to non-motile cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in ciliary membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in motile cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in non-motile cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ADP-ribosylation factor-like protein 13A
    Names
    ADP ribosylation factor like GTPase 13A
    ADP-ribosylation factor-like 13A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024366.1 → NP_001019537.1  ADP-ribosylation factor-like protein 13A

      See identical proteins and their annotated locations for NP_001019537.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079325
      UniProtKB/Swiss-Prot
      Q6AXT3
      UniProtKB/TrEMBL
      A0A8I6ADN1
      Conserved Domains (1) summary
      cd04161
      Location:23 → 189
      Arl2l1_Arl13_like; Arl2-like protein 1 (Arl2l1) and Arl13

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      101673637..101699986
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008773430.4 → XP_008771652.1  ADP-ribosylation factor-like protein 13A isoform X2

      UniProtKB/TrEMBL
      A0A8I6ADN1, A0A8L2R0C8
      Related
      ENSRNOP00000069009.2, ENSRNOT00000085068.3
      Conserved Domains (2) summary
      cd04161
      Location:23 → 189
      Arl2l1_Arl13_like; Arl2-like protein 1 (Arl2l1) and Arl13
      COG1100
      Location:18 → 218
      Gem1; GTPase SAR1 family domain [General function prediction only]

    2. XM_039099979.2 → XP_038955907.1  ADP-ribosylation factor-like protein 13A isoform X1

      UniProtKB/Swiss-Prot
      Q6AXT3
      UniProtKB/TrEMBL
      A0A8I6ADN1
      Conserved Domains (1) summary
      cd04161
      Location:23 → 189
      Arl2l1_Arl13_like; Arl2-like protein 1 (Arl2l1) and Arl13
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AXT3.1 GenPept UniProtKB/Swiss-Prot:Q6AXT3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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