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    Fbxl13 F-box and leucine-rich repeat protein 13 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100125363, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fbxl13provided by RGD
    Official Full Name
    F-box and leucine-rich repeat protein 13provided by RGD
    Primary source
    RGD:1642425
    See related
    EnsemblRapid:ENSRNOG00000043035 AllianceGenome:RGD:1642425
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Orthologous to human FBXL13 (F-box and leucine rich repeat protein 13). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 115.9) and Lung (RPKM 19.6) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fbxl13 in Genome Data Viewer
    Location:
    4q11
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (14307032..14505491)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (13414880..13607079)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (10020349..10170012)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene N-acyl phosphatidylethanolamine phospholipase D Neighboring gene armadillo repeat containing 10 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene leucine rich repeat containing 17 Neighboring gene small nucleolar RNA SNORD86 Neighboring gene uncharacterized LOC134486551 Neighboring gene family with sequence similarity 185, member A Neighboring gene coiled-coil domain containing 146 Neighboring gene uncharacterized LOC120102212 Neighboring gene fibrinogen-like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system. Ebstein F, et al. Int J Biochem Cell Biol, 2009 May. PMID 19028597
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC95282

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    F-box and leucine-rich repeat protein 13
    Names
    F-box/LRR-repeat protein 13
    dynein regulatory complex subunit 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001103355.1 → NP_001096825.2  F-box and leucine-rich repeat protein 13

      Status: VALIDATED

      Source sequence(s)
      BC087158
      UniProtKB/TrEMBL
      A0A8I6A9P6
      Related
      ENSRNOP00000089912.1, ENSRNOT00000105478.2
      Conserved Domains (3) summary
      cd09293
      Location:308 → 477
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:333 → 358
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:242 → 288
      F-box-like; F-box-like

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      14307032..14505491
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039106881.2 → XP_038962809.1  F-box and leucine-rich repeat protein 13 isoform X1

      UniProtKB/TrEMBL
      A0A8I6GKU0
      Related
      ENSRNOP00000103430.1, ENSRNOT00000160911.1
      Conserved Domains (4) summary
      cd09293
      Location:525 → 733
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:567 → 592
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam08457
      Location:134 → 214
      Sfi1; Sfi1 spindle body protein
      pfam12937
      Location:242 → 286
      F-box-like

    2. XM_039106883.2 → XP_038962811.1  F-box and leucine-rich repeat protein 13 isoform X3

      UniProtKB/TrEMBL
      A0A8I6A9P6
      Conserved Domains (4) summary
      cd09293
      Location:525 → 733
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:567 → 592
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam08457
      Location:134 → 214
      Sfi1; Sfi1 spindle body protein
      pfam12937
      Location:242 → 286
      F-box-like

    3. XM_039106882.2 → XP_038962810.1  F-box and leucine-rich repeat protein 13 isoform X2

      Related
      ENSRNOP00000060954.5, ENSRNOT00000065039.5
      Conserved Domains (4) summary
      cd09293
      Location:525 → 705
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:488 → 513
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam08457
      Location:134 → 214
      Sfi1; Sfi1 spindle body protein
      pfam12937
      Location:242 → 286
      F-box-like

    4. XM_039106884.2 → XP_038962812.1  F-box and leucine-rich repeat protein 13 isoform X4

      UniProtKB/TrEMBL
      A0A8I6A9P6
      Related
      ENSRNOP00000110678.1, ENSRNOT00000143849.1
      Conserved Domains (4) summary
      cd09293
      Location:525 → 733
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:567 → 592
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam08457
      Location:134 → 214
      Sfi1; Sfi1 spindle body protein
      pfam12937
      Location:242 → 286
      F-box-like

    5. XM_039106885.2 → XP_038962813.1  F-box and leucine-rich repeat protein 13 isoform X5

      UniProtKB/TrEMBL
      A0A8I6A9P6
      Conserved Domains (4) summary
      cd09293
      Location:308 → 477
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:333 → 358
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam08457
      Location:134 → 214
      Sfi1; Sfi1 spindle body protein
      pfam12937
      Location:242 → 286
      F-box-like
    Nucleotide Protein Strain
    Heading Accession and Version

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