Fgfbp3 fibroblast growth factor binding protein 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Fgfbp3provided by RGD
Official Full Name: fibroblast growth factor binding protein 3provided by RGD
Primary source: RGD:1560326
See related: EnsemblRapid:ENSRNOG00000022796 AllianceGenome:RGD:1560326
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1560326
Summary: Predicted to enable fibroblast growth factor binding activity and heparin binding activity. Predicted to be involved in several processes, including adult behavior; positive regulation of ERK1 and ERK2 cascade; and positive regulation of nervous system process. Predicted to act upstream of or within positive regulation of fibroblast growth factor receptor signaling pathway and positive regulation of vascular permeability. Predicted to be located in extracellular region. Orthologous to human FGFBP3 (fibroblast growth factor binding protein 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 38.1), Muscle (RPKM 19.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q53

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (244056569..244058574, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (234644023..234646028, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (255555050..255557055, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables fibroblast growth factor binding	ISO Inferred from Sequence Orthology more info
enables growth factor binding	IBA Inferred from Biological aspect of Ancestor more info
enables heparin binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in adult behavior	ISO Inferred from Sequence Orthology more info
involved_in cell-cell signaling	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of ERK1 and ERK2 cascade	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of fibroblast growth factor receptor signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of nervous system process	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of vascular permeability	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in extracellular region	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: fibroblast growth factor-binding protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.