Trmt11 tRNA methyltransferase 11 homolog [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Trmt11provided by RGD
Official Full Name: tRNA methyltransferase 11 homologprovided by RGD
Primary source: RGD:727798
See related: EnsemblRapid:ENSRNOG00000014240 AllianceGenome:RGD:727798
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Mds024
Summary: Predicted to enable methyltransferase activity. Predicted to be involved in methylation and tRNA processing. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Orthologous to human TRMT11 (tRNA methyltransferase 11 homolog). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 26.7), Kidney (RPKM 25.1) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1p11

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (28873361..28928679)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (27054437..27109765)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (29432109..29576079)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables tRNA (guanine(10)-N2)-methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables tRNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in methylation	IEA Inferred from Electronic Annotation more info
involved_in tRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info	PubMed

General protein information

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Preferred Names: tRNA (guanine(10)-N2)-methyltransferase homolog

Names: putative RNA methylase MDS024; tRNA guanosine-2'-O-methyltransferase TRM11 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001429736.1 → NP_001416665.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform 2

Status: VALIDATED

Source sequence(s)

JAXUCZ010000001

UniProtKB/Swiss-Prot

Q7TNK6

UniProtKB/TrEMBL

A0A0G2JWR1
NM_001429737.1 → NP_001416666.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform 3

Status: VALIDATED

Source sequence(s)

JAXUCZ010000001

UniProtKB/Swiss-Prot

Q7TNK6
NM_001429738.1 → NP_001416667.1 tRNA (guanine(10)-N2)-methyltransferase homolog isoform 4

Status: VALIDATED

Source sequence(s)

JAXUCZ010000001
NM_198051.3 → NP_932168.3 tRNA (guanine(10)-N2)-methyltransferase homolog isoform 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000001

UniProtKB/Swiss-Prot

Q7TNK6

UniProtKB/TrEMBL

A6JUS6, F1MA13

Related

ENSRNOP00000105205.1, ENSRNOT00000139645.1