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    Cd5 Cd5 molecule [ Rattus norvegicus (Norway rat) ]

    Gene ID: 54236, updated on 9-Dec-2024

    Summary

    Symbol
    Cd5provided by RGD
    Full Name
    Cd5 moleculeprovided by RGD
    Primary source
    RGD:2309
    See related
    EnsemblRapid:ENSRNOG00000020872 AllianceGenome:RGD:2309
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in T cell costimulation. Predicted to act upstream of or within apoptotic signaling pathway. Located in cell surface. Orthologous to human CD5 (CD5 molecule). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 396.4), Spleen (RPKM 70.5) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Cd5 in Genome Data Viewer
    Location:
    1q43
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (216790245..216811209, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (207365337..207386313, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (226770912..226791861, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene von Willebrand factor C and EGF domains Neighboring gene pepsinogen A3 Neighboring gene VPS37C subunit of ESCRT-I Neighboring gene uncharacterized LOC120099989 Neighboring gene transfer RNA alanine (anticodon AGC) 22 Neighboring gene Cd6 molecule

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    General gene information

    Clone Names

    • MGC114334

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in T cell costimulation  
    involved_in T cell costimulation  
    acts_upstream_of_or_within T cell costimulation  
    involved_in apoptotic signaling pathway  
    acts_upstream_of_or_within apoptotic signaling pathway  
    Component Evidence Code Pubs
    located_in cell surface PubMed 
    located_in external side of plasma membrane  
    located_in external side of plasma membrane  
    located_in membrane  
    is_active_in plasma membrane  
    located_in plasma membrane  

    General protein information

    Preferred Names
    T-cell surface glycoprotein CD5
    Names
    CD5 antigen
    Lymphocyte antigen CD5
    T-cell surface glycoprotein CD5-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019295.3NP_062168.2  T-cell surface glycoprotein CD5 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/Swiss-Prot
      P51882, Q63098
      UniProtKB/TrEMBL
      A0A8L2QP90, A6I055, A6I057
      Related
      ENSRNOP00000051697.4, ENSRNOT00000054812.6
      Conserved Domains (1) summary
      smart00202
      Location:46143
      SR; Scavenger receptor Cys-rich

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      216790245..216811209 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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