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    Sntn sentan, cilia apical structure protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498456, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sntnprovided by RGD
    Official Full Name
    sentan, cilia apical structure proteinprovided by RGD
    Primary source
    RGD:1562356
    See related
    EnsemblRapid:ENSRNOG00000027383 AllianceGenome:RGD:1562356
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562356
    Summary
    Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Predicted to be located in cilium. Orthologous to human SNTN (sentan, cilia apical structure protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 33.6) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Sntn in Genome Data Viewer
    Location:
    15p16
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (13943052..13956109, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (11512563..11525608, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (14497770..14510828, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein-like Neighboring gene PRELI domain containing 1, pseudogene 7 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene synaptoporin Neighboring gene ribosomal protein S20, pseudogene 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables calcium-dependent protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transition metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cilium ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109098.1NP_001102568.1  sentan

      See identical proteins and their annotated locations for NP_001102568.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474010
      UniProtKB/TrEMBL
      A6K081, F1LX90
      Related
      ENSRNOP00000034316.6, ENSRNOT00000039347.6
      Conserved Domains (1) summary
      cd00213
      Location:50134
      S-100; S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 proteins are ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      13943052..13956109 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039093581.2XP_038949509.1  sentan isoform X3

      Conserved Domains (1) summary
      cl08302
      Location:5092
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    2. XM_039093578.2XP_038949506.1  sentan isoform X1

      Conserved Domains (1) summary
      cd00213
      Location:892
      S-100; S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 proteins are ...
    3. XM_039093579.2XP_038949507.1  sentan isoform X1

      Conserved Domains (1) summary
      cd00213
      Location:892
      S-100; S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 proteins are ...
    4. XM_039093580.2XP_038949508.1  sentan isoform X2

      Conserved Domains (1) summary
      cl08302
      Location:5091
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...