Lyzl1 lysozyme-like 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Lyzl1provided by RGD
Official Full Name: lysozyme-like 1provided by RGD
Primary source: RGD:1559869
See related: AllianceGenome:RGD:1559869
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Lyzd1; RGD1559869
Summary: Predicted to enable lysozyme activity. Orthologous to several human genes including LYZL1 (lysozyme like 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 239.6) See more
Orthologs: human mouse all
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Genomic context

Location:: 17q12.1

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	17	NC_086035.1 (58225664..58239120, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	17	NC_051352.1 (53530437..53543877, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	17	NC_005116.4 (56255613..56269245, complement)

Chromosome 17 - NC_086035.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

this study indicates a role for LYZL1 protein in sperm function
Title: Immunization against lysozyme-like proteins affect sperm function and fertility in the rat.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables lysozyme activity	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: lysozyme-like protein 2

Names: lysozyme d1; lysozyme-like protein 1

NP_001102352.1

EC 3.2.1.17

XP_038951908.1

EC 3.2.1.17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001108882.1 → NP_001102352.1 lysozyme-like protein 2 precursor

See identical proteins and their annotated locations for NP_001102352.1

Status: PROVISIONAL

Source sequence(s)

CH474030

UniProtKB/TrEMBL

A6K9G4, D4A0W0

Conserved Domains (1) summary

cd00119
Location:20 → 143

LYZ1; C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have ...