Dnttip1 deoxynucleotidyltransferase, terminal, interacting protein 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Dnttip1provided by RGD
Official Full Name: deoxynucleotidyltransferase, terminal, interacting protein 1provided by RGD
Primary source: RGD:621627
See related: EnsemblRapid:ENSRNOG00000014933 AllianceGenome:RGD:621627
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable DNA binding activity; nucleosome binding activity; and protein homodimerization activity. Predicted to be located in chromosome; nucleolus; and nucleoplasm. Predicted to be part of histone deacetylase complex. Predicted to be active in nucleus. Orthologous to human DNTTIP1 (deoxynucleotidyltransferase terminal interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Kidney (RPKM 92.6), Testes (RPKM 78.6) and 9 other tissues See more
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 3q42

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (173901070..173924742)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (153481718..153505403)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (161212156..161235749)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA binding	ISO Inferred from Sequence Orthology more info
enables DNA binding	ISS Inferred from Sequence or Structural Similarity more info
enables nucleosome binding	IBA Inferred from Biological aspect of Ancestor more info
enables nucleosome binding	IEA Inferred from Electronic Annotation more info
enables nucleosome binding	ISO Inferred from Sequence Orthology more info
enables nucleosome binding	ISS Inferred from Sequence or Structural Similarity more info
enables protein homodimerization activity	IEA Inferred from Electronic Annotation more info
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in chromosome	IEA Inferred from Electronic Annotation more info
located_in chromosome	ISO Inferred from Sequence Orthology more info
part_of histone deacetylase complex	IEA Inferred from Electronic Annotation more info
part_of histone deacetylase complex	ISO Inferred from Sequence Orthology more info
part_of histone deacetylase complex	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

Go to the top of the page Help

Preferred Names: deoxynucleotidyltransferase terminal-interacting protein 1

Names: tdIF1; tdT-interacting factor 1; terminal deoxynucleotidyltransferase-interacting factor 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_134400.2 → NP_599227.2 deoxynucleotidyltransferase terminal-interacting protein 1

See identical proteins and their annotated locations for NP_599227.2

Status: VALIDATED

Source sequence(s)

BC100640

UniProtKB/Swiss-Prot

Q91Y53

UniProtKB/TrEMBL

Q497A7

Related

ENSRNOP00000103422.1, ENSRNOT00000162591.1

Conserved Domains (1) summary

pfam18192
Location:65 → 132

DNTTIP1_dimer; DNTTIP1 dimerisation domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086021.1 Reference GRCr8

Range

173901070..173924742

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039104212.2 → XP_038960140.1 deoxynucleotidyltransferase terminal-interacting protein 1 isoform X3

Conserved Domains (1) summary

pfam18192
Location:65 → 125

DNTTIP1_dimer; DNTTIP1 dimerisation domain
XM_039104210.2 → XP_038960138.1 deoxynucleotidyltransferase terminal-interacting protein 1 isoform X1

UniProtKB/Swiss-Prot

Q91Y53

Related

ENSRNOP00000108339.1, ENSRNOT00000150206.1

Conserved Domains (1) summary

pfam18192
Location:65 → 132

DNTTIP1_dimer; DNTTIP1 dimerisation domain
XM_039104211.2 → XP_038960139.1 deoxynucleotidyltransferase terminal-interacting protein 1 isoform X2

UniProtKB/Swiss-Prot

Q91Y53

Conserved Domains (1) summary

pfam18192
Location:25 → 92

DNTTIP1_dimer; DNTTIP1 dimerisation domain