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    Slc2a6 solute carrier family 2 member 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296600, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Slc2a6provided by RGD
    Official Full Name
    solute carrier family 2 member 6provided by RGD
    Primary source
    RGD:1309317
    See related
    EnsemblRapid:ENSRNOG00000005900 AllianceGenome:RGD:1309317
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in regulation of glycolytic process. Predicted to be located in lysosomal membrane. Orthologous to human SLC2A6 (solute carrier family 2 member 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 93.8), Adrenal (RPKM 72.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Slc2a6 in Genome Data Viewer
    Location:
    3p12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (30746472..30753287, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (10348395..10355208, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (5567729..5575144, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene REX4 homolog, 3'-5' exonuclease Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif, 13 Neighboring gene uncharacterized LOC102548484 Neighboring gene calcium channel flower domain containing 1 Neighboring gene myomaker, myoblast fusion factor Neighboring gene ADAMTS-like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. GLUT6 is a lysosomal transporter that is regulated by inflammatory stimuli and modulates glycolysis in macrophages. Maedera S, et al. FEBS Lett, 2019 Jan. PMID 30431159
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    NOT enables D-glucose transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    NOT involved_in D-glucose transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of glycolytic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    solute carrier family 2, facilitated glucose transporter member 6
    Names
    solute carrier family 2 (facilitated glucose transporter), member 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001429160.1 → NP_001416089.1  solute carrier family 2, facilitated glucose transporter member 6 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003

    2. NM_001429161.1 → NP_001416090.1  solute carrier family 2, facilitated glucose transporter member 6 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003

    3. NM_001429162.1 → NP_001416091.1  solute carrier family 2, facilitated glucose transporter member 6 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      30746472..30753287 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063283473.1 → XP_063139543.1  solute carrier family 2, facilitated glucose transporter member 6 isoform X2

      Related
      ENSRNOP00000105485.1, ENSRNOT00000150537.1

    2. XM_063283475.1 → XP_063139545.1  solute carrier family 2, facilitated glucose transporter member 6 isoform X4

    3. XM_063283474.1 → XP_063139544.1  solute carrier family 2, facilitated glucose transporter member 6 isoform X3

    4. XM_063283472.1 → XP_063139542.1  solute carrier family 2, facilitated glucose transporter member 6 isoform X1

    5. XM_063283476.1 → XP_063139546.1  solute carrier family 2, facilitated glucose transporter member 6 isoform X5

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001106562.1: Suppressed sequence

      Description
      NM_001106562.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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