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    Wdr86 WD repeat domain 86 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 311956, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Wdr86provided by RGD
    Official Full Name
    WD repeat domain 86provided by RGD
    Primary source
    RGD:1566180
    See related
    EnsemblRapid:ENSRNOG00000025735 AllianceGenome:RGD:1566180
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1566180
    Summary
    Orthologous to human WDR86 (WD repeat domain 86). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 29.3), Uterus (RPKM 24.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Wdr86 in Genome Data Viewer
    Location:
    4q11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (11315826..11335932)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (10423496..10443473)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (6942415..6948912)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene crystallin, gamma N Neighboring gene negative regulator of ubiquitin-like proteins 1 Neighboring gene uncharacterized LOC134486541 Neighboring gene glycerol-3-phosphate dehydrogenase 1 like 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    WD repeat-containing protein 86

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395636.1 → NP_001382565.1  WD repeat-containing protein 86

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A0A0G2K7Z2
      Related
      ENSRNOP00000074405.1, ENSRNOT00000079770.3
      Conserved Domains (3) summary
      smart00320
      Location:304 → 341
      WD40; WD40 repeats
      cd00200
      Location:8 → 301
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:101 → 135
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      11315826..11335932
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063285941.1 → XP_063142011.1  WD repeat-containing protein 86 isoform X1

    RNA

    1. XR_005504115.2 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001110489.1: Suppressed sequence

      Description
      NM_001110489.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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