U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Cfap206 cilia and flagella associated protein 206 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 366347, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Cfap206provided by RGD
    Official Full Name
    cilia and flagella associated protein 206provided by RGD
    Primary source
    RGD:1310641
    See related
    EnsemblRapid:ENSRNOG00000009061 AllianceGenome:RGD:1310641
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310641
    Summary
    Predicted to be involved in regulation of cilium beat frequency; regulation of flagellated sperm motility; and sperm axoneme assembly. Predicted to be located in A axonemal microtubule and motile cilium. Predicted to be part of radial spoke. Predicted to be active in axoneme and ciliary basal body. Orthologous to human CFAP206 (cilia and flagella associated protein 206). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 438.0) See more
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Cfap206 in Genome Data Viewer
    Location:
    5q21
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (54050697..54095438, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (49254399..49299145, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (50148685..50193580, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene origin recognition complex, subunit 3 Neighboring gene arginyl-tRNA synthetase 2, mitochondrial Neighboring gene solute carrier family 35 member A1 Neighboring gene similar to human chromosome 6 open reading frame 163 Neighboring gene small integral membrane protein 8

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, et al. Nature, 2004 Apr 1. PMID 15057822
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in axoneme assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in cilium movement ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of cilium beat frequency IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of cilium beat frequency IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of cilium beat frequency ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of cilium beat frequency ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of flagellated sperm motility IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of flagellated sperm motility IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of flagellated sperm motility ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of flagellated sperm motility ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in sperm axoneme assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sperm axoneme assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sperm axoneme assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in sperm axoneme assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in A axonemal microtubule ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in axoneme IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in axoneme IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in axoneme ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in axoneme ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ciliary basal body IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in ciliary basal body ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in motile cilium ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of radial spoke ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    cilia- and flagella-associated protein 206
    Names
    UPF0704 protein C6orf165 homolog

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079701.1 → NP_001073169.1  cilia- and flagella-associated protein 206

      See identical proteins and their annotated locations for NP_001073169.1

      Status: PROVISIONAL

      Source sequence(s)
      BC128759
      UniProtKB/Swiss-Prot
      A1A5Q4
      UniProtKB/TrEMBL
      A0A8I6A101
      Related
      ENSRNOP00000045325.3, ENSRNOT00000051243.6
      Conserved Domains (1) summary
      pfam12018
      Location:215 → 491
      FAP206; Domain of unknown function

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      54050697..54095438 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017593533.3 → XP_017449022.1  cilia- and flagella-associated protein 206 isoform X2

      UniProtKB/TrEMBL
      A0A8I6A101
      Related
      ENSRNOP00000085122.2, ENSRNOT00000114239.2

    2. XM_063288106.1 → XP_063144176.1  cilia- and flagella-associated protein 206 isoform X2

      UniProtKB/TrEMBL
      A0A8I6A101

    3. XM_017593532.3 → XP_017449021.1  cilia- and flagella-associated protein 206 isoform X1

      UniProtKB/Swiss-Prot
      A1A5Q4
      UniProtKB/TrEMBL
      A0A8I6A101
      Conserved Domains (1) summary
      pfam12018
      Location:215 → 491
      FAP206; Domain of unknown function

    4. XM_063288107.1 → XP_063144177.1  cilia- and flagella-associated protein 206 isoform X3

    5. XM_006237999.5 → XP_006238061.1  cilia- and flagella-associated protein 206 isoform X3

      See identical proteins and their annotated locations for XP_006238061.1

      Conserved Domains (1) summary
      pfam12018
      Location:217 → 490
      DUF3508; Domain of unknown function (DUF3508)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1A5Q4.1 GenPept UniProtKB/Swiss-Prot:A1A5Q4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools