Gpaa1 glycosylphosphatidylinositol anchor attachment 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Gpaa1provided by RGD
Official Full Name: glycosylphosphatidylinositol anchor attachment 1provided by RGD
Primary source: RGD:1303197
See related: EnsemblRapid:ENSRNOG00000029280 AllianceGenome:RGD:1303197
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable GPI-anchor transamidase activity. Predicted to contribute to GPI anchor binding activity. Predicted to be involved in attachment of GPI anchor to protein and protein-containing complex assembly. Predicted to be located in several cellular components, including centrosome; endoplasmic reticulum; and mitochondrion. Predicted to be part of GPI-anchor transamidase complex. Orthologous to human GPAA1 (glycosylphosphatidylinositol anchor attachment 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Kidney (RPKM 141.0), Thymus (RPKM 121.0) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 7q34

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (109932556..109936139)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (108051896..108055479)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (117394367..117397950)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
contributes_to GPI anchor binding	ISO Inferred from Sequence Orthology more info
enables GPI-anchor transamidase activity	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in GPI anchor biosynthetic process	TAS Traceable Author Statement more info	PubMed
involved_in attachment of GPI anchor to protein	IBA Inferred from Biological aspect of Ancestor more info
involved_in attachment of GPI anchor to protein	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of GPI-anchor transamidase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of GPI-anchor transamidase complex	ISO Inferred from Sequence Orthology more info
part_of GPI-anchor transamidase complex	TAS Traceable Author Statement more info	PubMed
located_in centrosome	IEA Inferred from Electronic Annotation more info
located_in centrosome	ISO Inferred from Sequence Orthology more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: glycosylphosphatidylinositol anchor attachment 1 protein

Names: GPI anchor attachment protein 1; anchor attachment protein 1; glycosylphosphatidylinositol anchor attachment protein 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.