C11h22orf39 similar to human chromosome 22 open reading frame 39 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: C11h22orf39provided by RGD
Official Full Name: similar to human chromosome 22 open reading frame 39provided by RGD
Primary source: RGD:1595717
See related: AllianceGenome:RGD:1595717
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in negative regulation of long-term synaptic potentiation. Predicted to be located in mitochondrion; synapse; and synaptic cleft. Orthologous to human C22orf39 (chromosome 22 open reading frame 39). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 45.3), Heart (RPKM 45.1) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 11q23

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	11	NC_086029.1 (95660135..95665750, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	11	NC_051346.1 (82155992..82160235, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	11	NC_005110.4 (86299210..86303453, complement)

Chromosome 11 - NC_086029.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in negative regulation of long-term synaptic potentiation	ISO Inferred from Sequence Orthology more info
involved_in regulation of synaptic plasticity	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in mitochondrion	ISO Inferred from Sequence Orthology more info	PubMed
located_in synapse	ISO Inferred from Sequence Orthology more info
located_in synaptic cleft	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: UPF0545 protein C22orf39 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001109058.1 → NP_001102528.1 UPF0545 protein C22orf39 homolog

See identical proteins and their annotated locations for NP_001102528.1

Status: PROVISIONAL

Source sequence(s)

CH473999

UniProtKB/TrEMBL

A6JSE6

Conserved Domains (1) summary

pfam11326
Location:13 → 88

DUF3128; Protein of unknown function (DUF3128)