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    Slc27a6 solute carrier family 27 member 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291582, updated on 9-Dec-2024

    Summary

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    Symbol
    Slc27a6provided by RGD
    Full Name
    solute carrier family 27 member 6provided by RGD
    Primary source
    RGD:1311977
    See related
    EnsemblRapid:ENSRNOG00000058193 AllianceGenome:RGD:1311977
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable long-chain fatty acid transmembrane transporter activity; long-chain fatty acid-CoA ligase activity; and very long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid import into cell and long-chain fatty acid metabolic process. Predicted to be active in endoplasmic reticulum membrane and plasma membrane. Biomarker of myocardial infarction. Orthologous to human SLC27A6 (solute carrier family 27 member 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 214.3), Lung (RPKM 85.2) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Slc27a6 in Genome Data Viewer
    Location:
    18q12.1
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (54238697..54297595)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (52040241..52099622)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (53609497..53667833)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102548224 Neighboring gene uncharacterized LOC120098199 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene isochorismatase domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fatty acid transporter levels and palmitate oxidation rate correlate with ejection fraction in the infarcted rat heart. Heather LC, et al. Cardiovasc Res, 2006 Dec 1. PMID 17034771
    2. Functional domains of the fatty acid transport proteins: studies using protein chimeras. DiRusso CC, et al. Biochim Biophys Acta, 2008 Mar. PMID 18258213, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables long-chain fatty acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables long-chain fatty acid-CoA ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables very long-chain fatty acid-CoA ligase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in long-chain fatty acid import into cell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in long-chain fatty acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    long-chain fatty acid transport protein 6
    Names
    long-chain fatty acid transport protein 6-like
    solute carrier family 27 (fatty acid transporter), member 6
    NP_001099615.1
    XP_038952625.1
    XP_038952626.1
    XP_063133282.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106145.1 → NP_001099615.1  long-chain fatty acid transport protein 6

      See identical proteins and their annotated locations for NP_001099615.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473971
      UniProtKB/TrEMBL
      A6IX92, D4A2B8
      Related
      ENSRNOP00000069400.1, ENSRNOT00000077443.3
      Conserved Domains (1) summary
      cl17068
      Location:75 → 609
      AFD_class_I; Adenylate forming domain, Class I superfamily

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      54238697..54297595
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063277212.1 → XP_063133282.1  long-chain fatty acid transport protein 6 isoform X3

    2. XM_039096697.2 → XP_038952625.1  long-chain fatty acid transport protein 6 isoform X1

      Conserved Domains (1) summary
      cl17068
      Location:75 → 487
      AFD_class_I; Adenylate forming domain, Class I superfamily

    3. XM_039096698.2 → XP_038952626.1  long-chain fatty acid transport protein 6 isoform X2

      Conserved Domains (1) summary
      cl17068
      Location:38 → 365
      AFD_class_I; Adenylate forming domain, Class I superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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