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    Plxdc1 plexin domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303505, updated on 9-Dec-2024

    Summary

    Official Symbol
    Plxdc1provided by RGD
    Official Full Name
    plexin domain containing 1provided by RGD
    Primary source
    RGD:1307496
    See related
    EnsemblRapid:ENSRNOG00000021536 AllianceGenome:RGD:1307496
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tem7; Arl12
    Summary
    Involved in spinal cord development. Located in dendrite and neuronal cell body. Orthologous to human PLXDC1 (plexin domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 31.7), Brain (RPKM 21.1) and 7 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Plxdc1 in Genome Data Viewer
    Location:
    10q31
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (83418837..83478451, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (82922499..82982124, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (85871122..85938085, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene LIM and SH3 protein 1 Neighboring gene F-box protein 47 Neighboring gene U7 small nuclear RNA Neighboring gene transfer RNA cysteine (anticodon GCA) 36 Neighboring gene transfer RNA cysteine (anticodon GCA) 37

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in spinal cord development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of receptor complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    plexin domain-containing protein 1
    Names
    ADP-ribosylation factor-like 12
    tumor endothelial marker7

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107046.1NP_001100516.1  plexin domain-containing protein 1 precursor

      See identical proteins and their annotated locations for NP_001100516.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473948
      UniProtKB/TrEMBL
      A6HIP0, D3ZEE4
      Related
      ENSRNOP00000050771.5, ENSRNOT00000043561.5
      Conserved Domains (2) summary
      pfam01437
      Location:304348
      PSI; Plexin repeat
      cl02648
      Location:165259
      NIDO; Nidogen-like

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      83418837..83478451 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)