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    Stfa3l1 stefin A3-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 408215, updated on 9-Dec-2024

    Summary

    Symbol
    Stfa3l1provided by RGD
    Full Name
    stefin A3-like 1provided by RGD
    Primary source
    RGD:1302997
    See related
    EnsemblRapid:ENSRNOG00000030984 AllianceGenome:RGD:1302997
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable cysteine-type endopeptidase inhibitor activity. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in peeling skin syndrome 4. Orthologous to human CSTA (cystatin A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See Stfa3l1 in Genome Data Viewer
    Location:
    11q22
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (78114013..78121232, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (64608683..64615902, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (67543578..67551211, complement)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene stefin A2 Neighboring gene stefin A2-like 3 Neighboring gene uncharacterized LOC134481076 Neighboring gene U6 spliceosomal RNA Neighboring gene cystatin A

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009177.1NP_001009177.1  stefin A3-like 1 precursor

      See identical proteins and their annotated locations for NP_001009177.1

      Status: PROVISIONAL

      Source sequence(s)
      BN000375
      UniProtKB/TrEMBL
      Q6IE18
      Related
      ENSRNOP00000046588.1, ENSRNOT00000049463.3
      Conserved Domains (1) summary
      pfam00031
      Location:43106
      Cystatin; Cystatin domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      78114013..78121232 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)