Etfa electron transfer flavoprotein subunit alpha [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Etfaprovided by RGD
Official Full Name: electron transfer flavoprotein subunit alphaprovided by RGD
Primary source: RGD:628747
See related: EnsemblRapid:ENSRNOG00000015233 AllianceGenome:RGD:628747
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: ETF
Summary: Predicted to enable electron transfer activity; flavin adenine dinucleotide binding activity; and oxidoreductase activity. Predicted to be involved in amino acid catabolic process; fatty acid beta-oxidation using acyl-CoA dehydrogenase; and respiratory electron transport chain. Predicted to be located in mitochondrial matrix. Predicted to be part of electron transfer flavoprotein complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in multiple acyl-CoA dehydrogenase deficiency. Orthologous to human ETFA (electron transfer flavoprotein subunit alpha). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Heart (RPKM 2288.1), Liver (RPKM 1495.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q24

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (64731192..64787965, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (55835115..55891890, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (60028786..60086352, complement)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables electron transfer activity	IBA Inferred from Biological aspect of Ancestor more info
enables electron transfer activity	IEA Inferred from Electronic Annotation more info
enables electron transfer activity	ISO Inferred from Sequence Orthology more info
enables electron transfer activity	ISS Inferred from Sequence or Structural Similarity more info
enables electron transfer activity	NAS Non-traceable Author Statement more info	PubMed
enables flavin adenine dinucleotide binding	IBA Inferred from Biological aspect of Ancestor more info
enables flavin adenine dinucleotide binding	IEA Inferred from Electronic Annotation more info
enables flavin adenine dinucleotide binding	ISO Inferred from Sequence Orthology more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in amino acid catabolic process	IEA Inferred from Electronic Annotation more info
involved_in amino acid catabolic process	ISO Inferred from Sequence Orthology more info
involved_in biological_process	ND No biological Data available more info
involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase	IBA Inferred from Biological aspect of Ancestor more info
involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase	IEA Inferred from Electronic Annotation more info
involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase	ISO Inferred from Sequence Orthology more info
involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase	ISS Inferred from Sequence or Structural Similarity more info
involved_in respiratory electron transport chain	IEA Inferred from Electronic Annotation more info
involved_in respiratory electron transport chain	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of electron transfer flavoprotein complex	IEA Inferred from Electronic Annotation more info
part_of electron transfer flavoprotein complex	ISO Inferred from Sequence Orthology more info
located_in mitochondrial matrix	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: electron transfer flavoprotein subunit alpha, mitochondrial

Names: alpha-ETF; electron transfer flavoprotein alpha subunit; electron transferring flavoprotein, alpha polypeptide; electron-transfer-flavoprotein, alpha polypeptide

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.