U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Cd248 CD248 molecule [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293669, updated on 9-Dec-2024

    Summary

    Symbol
    Cd248provided by RGD
    Full Name
    CD248 moleculeprovided by RGD
    Primary source
    RGD:1310404
    See related
    EnsemblRapid:ENSRNOG00000020197 AllianceGenome:RGD:1310404
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Cd164l1
    Summary
    Predicted to enable extracellular matrix binding activity and extracellular matrix protein binding activity. Predicted to be involved in cell migration. Predicted to act upstream of or within several processes, including fibroblast migration; lymph node development; and positive regulation of endothelial cell apoptotic process. Predicted to be located in cytoplasm. Predicted to be active in external side of plasma membrane. Orthologous to human CD248 (CD248 molecule). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Cd248 in Genome Data Viewer
    Location:
    1q43
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (211803052..211805616)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (202373676..202376240)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (220353308..220355872)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene BRMS1, transcriptional repressor and anoikis regulator Neighboring gene Ras and Rab interactor 1 Neighboring gene transmembrane protein 151A Neighboring gene Yip1 interacting factor homolog A, membrane trafficking protein

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calcium ion binding  
    enables carbohydrate binding  
    enables extracellular matrix binding  
    enables extracellular matrix binding  
    enables extracellular matrix protein binding  
    Component Evidence Code Pubs
    located_in cytoplasm  
    is_active_in external side of plasma membrane  

    General protein information

    Preferred Names
    endosialin
    Names
    CD164 sialomucin-like 1
    CD248 antigen, endosialin
    CD248 molecule, endosialin
    endosialin-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106325.1 → NP_001099795.1  endosialin precursor

      See identical proteins and their annotated locations for NP_001099795.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473953
      UniProtKB/TrEMBL
      A6HZ21, D3ZN06
      Related
      ENSRNOP00000027339.3, ENSRNOT00000027339.6
      Conserved Domains (3) summary
      cd03600
      Location:29 → 160
      CLECT_thrombomodulin_like; C-type lectin-like domain (CTLD) of the type found in human thrombomodulin(TM), Endosialin, C14orf27, and C1qR
      smart00179
      Location:312 → 350
      EGF_CA; Calcium-binding EGF-like domain
      pfam14670
      Location:235 → 271
      FXa_inhibition; Coagulation Factor Xa inhibitory site

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      211803052..211805616
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Loading
    External link. Please review our privacy policy.