U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Psmd11 proteasome 26S subunit, non-ATPase 11 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303353, updated on 9-Dec-2024

    Summary

    Official Symbol
    Psmd11provided by RGD
    Official Full Name
    proteasome 26S subunit, non-ATPase 11provided by RGD
    Primary source
    RGD:1306450
    See related
    EnsemblRapid:ENSRNOG00000005538 AllianceGenome:RGD:1306450
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable structural molecule activity. Predicted to be involved in proteasome assembly; stem cell differentiation; and ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol and nucleus. Predicted to be part of proteasome regulatory particle, lid subcomplex. Orthologous to human PSMD11 (proteasome 26S subunit, non-ATPase 11). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 190.0), Liver (RPKM 173.3) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Psmd11 in Genome Data Viewer
    Location:
    10q26
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (65923669..65977523)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (65433853..65479774)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (67810655..67857562)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene similar to human chromosome 17 open reading frame 75 Neighboring gene microRNA 632 Neighboring gene zinc finger protein 207 Neighboring gene cyclin-dependent kinase 5 regulatory subunit 1 like Neighboring gene cyclin-dependent kinase 5 regulatory subunit 1 Neighboring gene myosin ID Neighboring gene uncharacterized LOC134480833

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural molecule activity  
    Process Evidence Code Pubs
    involved_in proteasome assembly  
    involved_in proteasome assembly  
    involved_in proteasome assembly  
    involved_in stem cell differentiation  
    involved_in stem cell differentiation  
    involved_in stem cell differentiation  
    involved_in ubiquitin-dependent protein catabolic process  
    involved_in ubiquitin-dependent protein catabolic process  
    involved_in ubiquitin-dependent protein catabolic process  
    involved_in ubiquitin-dependent protein catabolic process  
    Component Evidence Code Pubs
    located_in cytosol  
    located_in nucleus  
    part_of proteasome accessory complex  
    part_of proteasome accessory complex  
    part_of proteasome complex  
    part_of proteasome complex  
    part_of proteasome regulatory particle  
    part_of proteasome regulatory particle  
    part_of proteasome regulatory particle, lid subcomplex  

    General protein information

    Preferred Names
    26S proteasome non-ATPase regulatory subunit 11
    Names
    26S proteasome regulatory subunit RPN6
    proteasome (prosome, macropain) 26S subunit, non-ATPase, 11

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001394006.1NP_001380935.1  26S proteasome non-ATPase regulatory subunit 11

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/Swiss-Prot
      F1LMZ8
      UniProtKB/TrEMBL
      B5DEP6
      Related
      ENSRNOP00000062146.2, ENSRNOT00000064285.4
      Conserved Domains (1) summary
      COG5159
      Location:17421
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]

    RNA

    1. NR_172065.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      65923669..65977523
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063269077.1XP_063125147.1  26S proteasome non-ATPase regulatory subunit 11 isoform X1

      UniProtKB/TrEMBL
      A0A0G2JWX1, A0A8I5ZWU3, A6HHB7
    2. XM_006246988.4XP_006247050.1  26S proteasome non-ATPase regulatory subunit 11 isoform X1

      See identical proteins and their annotated locations for XP_006247050.1

      UniProtKB/TrEMBL
      A0A0G2JWX1, A0A8I5ZWU3, A6HHB7
      Conserved Domains (2) summary
      COG5159
      Location:95499
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
      pfam01399
      Location:363467
      PCI; PCI domain
    3. XM_006246987.4XP_006247049.1  26S proteasome non-ATPase regulatory subunit 11 isoform X1

      See identical proteins and their annotated locations for XP_006247049.1

      UniProtKB/TrEMBL
      A0A0G2JWX1, A0A8I5ZWU3, A6HHB7
      Related
      ENSRNOP00000070048.1, ENSRNOT00000079156.3
      Conserved Domains (2) summary
      COG5159
      Location:95499
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
      pfam01399
      Location:363467
      PCI; PCI domain
    4. XM_063269078.1XP_063125148.1  26S proteasome non-ATPase regulatory subunit 11 isoform X2

    External link. Please review our privacy policy.