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    Hhatl hedgehog acyltransferase-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 301073, updated on 9-Dec-2024

    Summary

    Official Symbol
    Hhatlprovided by RGD
    Official Full Name
    hedgehog acyltransferase-likeprovided by RGD
    Primary source
    RGD:1311911
    See related
    EnsemblRapid:ENSRNOG00000019404 AllianceGenome:RGD:1311911
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Gup1; RGD1311911
    Summary
    Predicted to be involved in negative regulation of N-terminal protein palmitoylation. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in endoplasmic reticulum. Orthologous to human HHATL (hedgehog acyltransferase like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 490.7), Heart (RPKM 338.3) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Hhatl in Genome Data Viewer
    Location:
    8q32
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (130324510..130331580, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (121447001..121454070, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (130422071..130429205, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 47 Neighboring gene kelch-like family member 40 Neighboring gene coiled-coil domain containing 13 Neighboring gene HIG1 hypoxia inducible domain family, member 1A Neighboring gene atypical chemokine receptor 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum  
    located_in endoplasmic reticulum  
    located_in membrane  
    located_in perinuclear region of cytoplasm  

    General protein information

    Preferred Names
    protein-cysteine N-palmitoyltransferase HHAT-like protein
    Names
    Gup1, glycerol uptake/transporter homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106868.1NP_001100338.1  protein-cysteine N-palmitoyltransferase HHAT-like protein

      See identical proteins and their annotated locations for NP_001100338.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473954
      UniProtKB/TrEMBL
      A0A8I6AP12, A6I460, D4A9P9
      Related
      ENSRNOP00000026261.4, ENSRNOT00000026261.8
      Conserved Domains (1) summary
      cl00738
      Location:130449
      MBOAT; membrane-bound O-acyltransferase family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      130324510..130331580 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006244091.5XP_006244153.1  protein-cysteine N-palmitoyltransferase HHAT-like protein isoform X2

      UniProtKB/TrEMBL
      A0A8I6AP12
      Related
      ENSRNOP00000095961.2, ENSRNOT00000110668.2
      Conserved Domains (1) summary
      cl00738
      Location:130437
      MBOAT; MBOAT, membrane-bound O-acyltransferase family
    2. XM_063265306.1XP_063121376.1  protein-cysteine N-palmitoyltransferase HHAT-like protein isoform X2

      UniProtKB/TrEMBL
      A0A8I6AP12
    3. XM_039081306.2XP_038937234.1  protein-cysteine N-palmitoyltransferase HHAT-like protein isoform X1

      UniProtKB/TrEMBL
      A0A8I6AP12, A6I460, D4A9P9
      Conserved Domains (1) summary
      cl00738
      Location:130449
      MBOAT; membrane-bound O-acyltransferase family

    RNA

    1. XR_005487804.2 RNA Sequence

    2. XR_005487803.2 RNA Sequence

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