Trir telomerase RNA component interacting RNase [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Trirprovided by RGD
Official Full Name: telomerase RNA component interacting RNaseprovided by RGD
Primary source: RGD:1564093
See related: EnsemblRapid:ENSRNOG00000003863 AllianceGenome:RGD:1564093
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1564093
Summary: Predicted to enable 3'-5' exonuclease activity and 5'-3' exonuclease activity. Predicted to be involved in rRNA catabolic process. Orthologous to human TRIR (telomerase RNA component interacting RNase). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 820.7), Kidney (RPKM 366.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 19q11

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	19	NC_086037.1 (40029952..40033368, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	19	NC_051354.1 (23125083..23128502, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	19	NC_005118.4 (26142720..26146136)

Chromosome 19 - NC_086037.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables 3'-5' exonuclease activity	IBA Inferred from Biological aspect of Ancestor more info
enables 3'-5' exonuclease activity	ISO Inferred from Sequence Orthology more info
enables 5'-3' exonuclease activity	IBA Inferred from Biological aspect of Ancestor more info
enables 5'-3' exonuclease activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in rRNA catabolic process	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: telomerase RNA component interacting RNase

Names: uncharacterized protein C19orf43 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001105946.1 → NP_001099416.1 telomerase RNA component interacting RNase

See identical proteins and their annotated locations for NP_001099416.1

Status: PROVISIONAL

Source sequence(s)

CH473972

UniProtKB/TrEMBL

A6IY38, D3ZGR7

Related

ENSRNOP00000005270.2, ENSRNOT00000005270.5

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086037.1 Reference GRCr8

Range

40029952..40033368 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063277833.1 → XP_063133903.1 telomerase RNA component interacting RNase isoform X2
XM_063277832.1 → XP_063133902.1 telomerase RNA component interacting RNase isoform X1