Arl8a ARF like GTPase 8A [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Arl8aprovided by RGD
Official Full Name: ARF like GTPase 8Aprovided by RGD
Primary source: RGD:1565940
See related: EnsemblRapid:ENSRNOG00000005988 AllianceGenome:RGD:1565940
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1565940
Summary: Predicted to enable GTP binding activity. Predicted to be involved in anterograde axonal transport. Predicted to be located in cytoplasm; midbody; and spindle midzone. Predicted to be active in lysosomal membrane. Orthologous to human ARL8A (ARF like GTPase 8A). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 270.3), Lung (RPKM 134.5) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 13q13

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	13	NC_086031.1 (49137632..49146633)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	13	NC_051348.1 (46585845..46594851)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	13	NC_005112.4 (51972974..51981976)

Chromosome 13 - NC_086031.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH135350 (e-PCR)
- UniSTS:218627

BE121320 (e-PCR)
- UniSTS:248067

RH137174 (e-PCR)
- UniSTS:219262

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables GTP binding	ISO Inferred from Sequence Orthology more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in anterograde axonal transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in anterograde axonal transport	ISO Inferred from Sequence Orthology more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in axon cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in late endosome membrane	IEA Inferred from Electronic Annotation more info
is_active_in lysosomal membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in midbody	ISO Inferred from Sequence Orthology more info
located_in spindle midzone	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: ADP-ribosylation factor-like protein 8A

Names: ADP-ribosylation factor like GTPase 8A; ADP-ribosylation factor-like 8A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.