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    Zfp280c zinc finger protein 280C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 302812, updated on 9-Dec-2024

    Summary

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    Symbol
    Zfp280cprovided by RGD
    Full Name
    zinc finger protein 280Cprovided by RGD
    Primary source
    RGD:1564669
    See related
    EnsemblRapid:ENSRNOG00000006797 AllianceGenome:RGD:1564669
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Suhw3; Zfp981; RGD1564669
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human ZNF280C (zinc finger protein 280C). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 56.8), Lung (RPKM 53.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp280c in Genome Data Viewer
    Location:
    Xq36
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (132594279..132685548, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (127716403..127807600, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (135371696..135434204, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene apoptosis inducing factor, mitochondria associated 1 Neighboring gene RAB33A, member RAS oncogene family Neighboring gene solute carrier family 25 member 14 Neighboring gene G protein-coupled receptor 119 Neighboring gene RNA binding motif protein, X-linked 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 280C
    Names
    suppressor of hairy wing homolog 3
    zinc finger protein 981

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427656.1 → NP_001414585.1  zinc finger protein 280C

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A0A8I6A8B8, A6JMQ8
      Related
      ENSRNOP00000095403.2, ENSRNOT00000110294.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      132594279..132685548 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039100526.2 → XP_038956454.1  zinc finger protein 280C isoform X1

      UniProtKB/TrEMBL
      A0A8I6A8B8, A6JMQ8
      Related
      ENSRNOP00000108807.1, ENSRNOT00000148417.1
      Conserved Domains (2) summary
      sd00017
      Location:368 → 389
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13836
      Location:62 → 237
      DUF4195; Domain of unknown function (DUF4195)

    2. XM_039100527.2 → XP_038956455.1  zinc finger protein 280C isoform X2

      UniProtKB/TrEMBL
      A6JMQ8, D3ZZ25
      Conserved Domains (2) summary
      sd00017
      Location:356 → 377
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13836
      Location:50 → 225
      DUF4195; Domain of unknown function (DUF4195)

    3. XM_063279953.1 → XP_063136023.1  zinc finger protein 280C isoform X1

      UniProtKB/TrEMBL
      A0A8I6A8B8, A6JMQ8

    4. XM_039100530.2 → XP_038956458.1  zinc finger protein 280C isoform X4

      UniProtKB/TrEMBL
      A6JMQ8
      Conserved Domains (2) summary
      sd00017
      Location:335 → 356
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13836
      Location:62 → 204
      DUF4195; Domain of unknown function (DUF4195)

    5. XM_008773541.3 → XP_008771763.1  zinc finger protein 280C isoform X2

      See identical proteins and their annotated locations for XP_008771763.1

      UniProtKB/TrEMBL
      A6JMQ8, D3ZZ25
      Related
      ENSRNOP00000051158.6, ENSRNOT00000044435.7
      Conserved Domains (2) summary
      sd00017
      Location:356 → 377
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13836
      Location:50 → 225
      DUF4195; Domain of unknown function (DUF4195)

    6. XM_039100528.2 → XP_038956456.1  zinc finger protein 280C isoform X3

      UniProtKB/TrEMBL
      A6JMQ8
      Conserved Domains (2) summary
      sd00017
      Location:342 → 363
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13836
      Location:36 → 211
      DUF4195; Domain of unknown function (DUF4195)

    7. XM_063279955.1 → XP_063136025.1  zinc finger protein 280C isoform X2

      UniProtKB/TrEMBL
      A6JMQ8, D3ZZ25

    8. XM_006257541.5 → XP_006257603.1  zinc finger protein 280C isoform X1

      See identical proteins and their annotated locations for XP_006257603.1

      UniProtKB/TrEMBL
      A0A8I6A8B8, A6JMQ8
      Conserved Domains (2) summary
      sd00017
      Location:368 → 389
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13836
      Location:62 → 237
      DUF4195; Domain of unknown function (DUF4195)

    9. XM_063279956.1 → XP_063136026.1  zinc finger protein 280C isoform X3

      UniProtKB/TrEMBL
      A6JMQ8
      Related
      ENSRNOP00000107950.1, ENSRNOT00000147647.1

    RNA

    1. XR_005498448.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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