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    St7l suppression of tumorigenicity 7-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 295344, updated on 9-Dec-2024

    Summary

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    Official Symbol
    St7lprovided by RGD
    Official Full Name
    suppression of tumorigenicity 7-likeprovided by RGD
    Primary source
    RGD:1359336
    See related
    EnsemblRapid:ENSRNOG00000014002 AllianceGenome:RGD:1359336
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in negative regulation of cell growth. Predicted to be located in membrane and ribosome. Predicted to be part of ribonucleoprotein complex. Orthologous to human ST7L (suppression of tumorigenicity 7 like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 71.7), Heart (RPKM 67.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See St7l in Genome Data Viewer
    Location:
    2q34
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (195052939..195122755)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (192364594..192434414)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (207350651..207421082)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene ras homolog family member C Neighboring gene Mov10 RNA helicase Neighboring gene capping actin protein of muscle Z-line subunit alpha 1 Neighboring gene Wnt family member 2B Neighboring gene small ribosomal subunit protein eS6-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. ST7-mediated suppression of tumorigenicity of prostate cancer cells is characterized by remodeling of the extracellular matrix. Hooi CF, et al. Oncogene, 2006 Jun 29. PMID 16474848
    2. Molecular cloning and characterization of mouse St7r (St7-like, St7l). Saitoh T, et al. Int J Mol Med, 2002 Jul. PMID 12060862
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC94245

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of cell growth IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of cell growth ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    suppressor of tumorigenicity 7 protein-like
    Names
    suppressor of tumorigenicity protein 7-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007639.1 → NP_001007640.1  suppressor of tumorigenicity 7 protein-like

      See identical proteins and their annotated locations for NP_001007640.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079194
      UniProtKB/Swiss-Prot
      Q68FW3
      UniProtKB/TrEMBL
      A0A0G2K7G8, A6K3Q1
      Related
      ENSRNOP00000109875.1, ENSRNOT00000158468.1
      Conserved Domains (1) summary
      cd11557
      Location:75 → 542
      ST7; Suppression of tumorigenicity 7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      195052939..195122755
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063281643.1 → XP_063137713.1  suppressor of tumorigenicity 7 protein-like isoform X1

    2. XM_063281644.1 → XP_063137714.1  suppressor of tumorigenicity 7 protein-like isoform X2

    3. XM_063281647.1 → XP_063137717.1  suppressor of tumorigenicity 7 protein-like isoform X4

    4. XM_063281646.1 → XP_063137716.1  suppressor of tumorigenicity 7 protein-like isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q68FW3.1 GenPept UniProtKB/Swiss-Prot:Q68FW3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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