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    Ccdc77 coiled-coil domain containing 77 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 312677, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ccdc77provided by RGD
    Official Full Name
    coiled-coil domain containing 77provided by RGD
    Primary source
    RGD:1310710
    See related
    EnsemblRapid:ENSRNOG00000037206 AllianceGenome:RGD:1310710
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310710
    Summary
    Predicted to be active in centrosome. Orthologous to human CCDC77 (coiled-coil domain containing 77). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 38.0), Thymus (RPKM 37.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ccdc77 in Genome Data Viewer
    Location:
    4q42
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (155206402..155238235, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (153534184..153566059, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (152860669..152892518, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486682 Neighboring gene transfer RNA leucine (anticodon AAG) 13 Neighboring gene lysine demethylase 5A Neighboring gene interleukin 17 receptor A Neighboring gene transmembrane protein 121B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. Jakobsen L, et al. EMBO J, 2011 Apr 20. PMID 21399614, Free PMC Article
    2. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 77

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191752.1 → NP_001178681.1  coiled-coil domain-containing protein 77

      See identical proteins and their annotated locations for NP_001178681.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A0A8I6GIA6, A6ILA2, D3ZHU5
      Conserved Domains (1) summary
      TIGR02168
      Location:212 → 486
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      155206402..155238235 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063286115.1 → XP_063142185.1  coiled-coil domain-containing protein 77 isoform X2

      UniProtKB/TrEMBL
      D3ZHU5

    2. XM_006237236.5 → XP_006237298.1  coiled-coil domain-containing protein 77 isoform X1

      UniProtKB/TrEMBL
      A0A8I6GCW0, D3ZHU5
      Related
      ENSRNOP00000110643.1, ENSRNOT00000169059.1
      Conserved Domains (1) summary
      COG1196
      Location:180 → 518
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    3. XM_063286118.1 → XP_063142188.1  coiled-coil domain-containing protein 77 isoform X5

      UniProtKB/TrEMBL
      D3ZHU5

    4. XM_006237244.5 → XP_006237306.1  coiled-coil domain-containing protein 77 isoform X5

      See identical proteins and their annotated locations for XP_006237306.1

      UniProtKB/TrEMBL
      D3ZHU5
      Conserved Domains (1) summary
      TIGR02168
      Location:183 → 452
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    5. XM_006237238.4 → XP_006237300.1  coiled-coil domain-containing protein 77 isoform X3

      See identical proteins and their annotated locations for XP_006237300.1

      UniProtKB/TrEMBL
      A0A8I6GIA6, A6ILA2, D3ZHU5
      Conserved Domains (1) summary
      TIGR02168
      Location:212 → 486
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    6. XM_006237239.4 → XP_006237301.1  coiled-coil domain-containing protein 77 isoform X3

      See identical proteins and their annotated locations for XP_006237301.1

      UniProtKB/TrEMBL
      A0A8I6GIA6, A6ILA2, D3ZHU5
      Related
      ENSRNOP00000099446.1, ENSRNOT00000137052.1
      Conserved Domains (1) summary
      TIGR02168
      Location:212 → 486
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    7. XM_008763246.3 → XP_008761468.1  coiled-coil domain-containing protein 77 isoform X4

      UniProtKB/TrEMBL
      D3ZHU5
      Related
      ENSRNOP00000085428.2, ENSRNOT00000112339.2
      Conserved Domains (1) summary
      COG1196
      Location:100 → 438
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    8. XM_039107656.2 → XP_038963584.1  coiled-coil domain-containing protein 77 isoform X3

      UniProtKB/TrEMBL
      A0A8I6GIA6, A6ILA2, D3ZHU5
      Related
      ENSRNOP00000089671.2, ENSRNOT00000100367.2
      Conserved Domains (1) summary
      TIGR02168
      Location:212 → 486
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    9. XM_063286116.1 → XP_063142186.1  coiled-coil domain-containing protein 77 isoform X3

      UniProtKB/TrEMBL
      A0A8I6GIA6, A6ILA2, D3ZHU5

    10. XM_063286117.1 → XP_063142187.1  coiled-coil domain-containing protein 77 isoform X3

      UniProtKB/TrEMBL
      A0A8I6GIA6, A6ILA2, D3ZHU5

    11. XM_039107654.2 → XP_038963582.1  coiled-coil domain-containing protein 77 isoform X3

      UniProtKB/TrEMBL
      A0A8I6GIA6, A6ILA2, D3ZHU5
      Related
      ENSRNOP00000053046.3, ENSRNOT00000056200.4
      Conserved Domains (1) summary
      TIGR02168
      Location:212 → 486
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    12. XM_006237243.5 → XP_006237305.1  coiled-coil domain-containing protein 77 isoform X5

      See identical proteins and their annotated locations for XP_006237305.1

      UniProtKB/TrEMBL
      D3ZHU5
      Conserved Domains (1) summary
      TIGR02168
      Location:183 → 452
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    13. XM_006237240.5 → XP_006237302.1  coiled-coil domain-containing protein 77 isoform X3

      See identical proteins and their annotated locations for XP_006237302.1

      UniProtKB/TrEMBL
      A0A8I6GIA6, A6ILA2, D3ZHU5
      Conserved Domains (1) summary
      TIGR02168
      Location:212 → 486
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    14. XM_039107653.2 → XP_038963581.1  coiled-coil domain-containing protein 77 isoform X3

      UniProtKB/TrEMBL
      A0A8I6GIA6, A6ILA2, D3ZHU5
      Conserved Domains (1) summary
      TIGR02168
      Location:212 → 486
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    15. XM_008763245.4 → XP_008761467.1  coiled-coil domain-containing protein 77 isoform X3

      See identical proteins and their annotated locations for XP_008761467.1

      UniProtKB/TrEMBL
      A0A8I6GIA6, A6ILA2, D3ZHU5
      Conserved Domains (1) summary
      TIGR02168
      Location:212 → 486
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    16. XM_039107655.2 → XP_038963583.1  coiled-coil domain-containing protein 77 isoform X3

      UniProtKB/TrEMBL
      A0A8I6GIA6, A6ILA2, D3ZHU5
      Conserved Domains (1) summary
      TIGR02168
      Location:212 → 486
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    17. XM_039107659.2 → XP_038963587.1  coiled-coil domain-containing protein 77 isoform X5

      UniProtKB/TrEMBL
      D3ZHU5
      Conserved Domains (1) summary
      TIGR02168
      Location:183 → 452
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RNA

    1. XR_005503234.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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