Cfap20 cilia and flagella associated protein 20 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cfap20provided by RGD
Official Full Name: cilia and flagella associated protein 20provided by RGD
Primary source: RGD:1308493
See related: EnsemblRapid:ENSRNOG00000042179 AllianceGenome:RGD:1308493
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Gtl3
Summary: Predicted to be involved in several processes, including positive regulation of feeding behavior; protein polyglutamylation; and regulation of cilium beat frequency involved in ciliary motility. Predicted to be located in axonemal microtubule; centriole; and nucleoplasm. Predicted to be active in axonemal B tubule inner sheath; ciliary basal body; and sperm flagellum. Orthologous to human CFAP20 (cilia and flagella associated protein 20). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 280.6), Lung (RPKM 179.9) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 19p13

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	19	NC_086037.1 (9614265..9628612)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	19	NC_051354.1 (9608867..9622558)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	19	NC_005118.4 (10024938..10038838)

Chromosome 19 - NC_086037.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in cilium assembly	IEA Inferred from Electronic Annotation more info
involved_in cilium assembly	ISO Inferred from Sequence Orthology more info
involved_in cilium assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in flagellated sperm motility	ISO Inferred from Sequence Orthology more info
involved_in flagellated sperm motility	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of cell motility	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of cell motility	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of cell motility	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cell motility	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of feeding behavior	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of feeding behavior	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of feeding behavior	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein polyglutamylation	ISO Inferred from Sequence Orthology more info
involved_in protein polyglutamylation	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of cilium beat frequency involved in ciliary motility	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of cilium beat frequency involved in ciliary motility	IEA Inferred from Electronic Annotation more info
involved_in regulation of cilium beat frequency involved in ciliary motility	ISO Inferred from Sequence Orthology more info
involved_in regulation of cilium beat frequency involved in ciliary motility	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in axonemal B tubule inner sheath	ISO Inferred from Sequence Orthology more info
located_in axonemal microtubule	IEA Inferred from Electronic Annotation more info
located_in axonemal microtubule	ISO Inferred from Sequence Orthology more info
located_in axonemal microtubule	ISS Inferred from Sequence or Structural Similarity more info
located_in centriole	IEA Inferred from Electronic Annotation more info
located_in centriole	ISO Inferred from Sequence Orthology more info
located_in centriole	ISS Inferred from Sequence or Structural Similarity more info
is_active_in ciliary basal body	IBA Inferred from Biological aspect of Ancestor more info
located_in ciliary basal body	IEA Inferred from Electronic Annotation more info
located_in ciliary basal body	ISO Inferred from Sequence Orthology more info
located_in ciliary basal body	ISS Inferred from Sequence or Structural Similarity more info
located_in cilium	IEA Inferred from Electronic Annotation more info
located_in cilium	ISO Inferred from Sequence Orthology more info
located_in cilium	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
is_active_in motile cilium	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
is_active_in sperm flagellum	ISO Inferred from Sequence Orthology more info
is_active_in sperm flagellum	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: cilia- and flagella-associated protein 20

Names: UPF0468 protein C16orf80 homolog; gene trap locus 3 protein homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001037978.2 → NP_001033067.1 cilia- and flagella-associated protein 20 isoform 2

See identical proteins and their annotated locations for NP_001033067.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000019

UniProtKB/Swiss-Prot

Q499T7

UniProtKB/TrEMBL

A0A8I5ZUW3

Conserved Domains (1) summary

pfam05018
Location:6 → 144

DUF667; Protein of unknown function (DUF667)
NM_001399181.1 → NP_001386110.1 cilia- and flagella-associated protein 20 isoform 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000019

UniProtKB/TrEMBL

A0A0H2UI05, A0A8I5ZUW3, A6JY06

Related

ENSRNOP00000058109.4, ENSRNOT00000061392.6

Conserved Domains (1) summary

pfam05018
Location:1 → 185

DUF667; Protein of unknown function (DUF667)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086037.1 Reference GRCr8

Range

9614265..9628612

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039097696.2 → XP_038953624.1 cilia- and flagella-associated protein 20 isoform X1

Conserved Domains (1) summary

pfam05018
Location:1 → 185

DUF667; Protein of unknown function (DUF667)