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    Slc45a4 solute carrier family 45, member 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315054, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Slc45a4provided by RGD
    Official Full Name
    solute carrier family 45, member 4provided by RGD
    Primary source
    RGD:1309971
    See related
    EnsemblRapid:ENSRNOG00000007818 AllianceGenome:RGD:1309971
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309971
    Summary
    Predicted to enable sucrose:proton symporter activity. Predicted to act upstream of or within sucrose transport. Predicted to be active in membrane. Orthologous to human SLC45A4 (solute carrier family 45 member 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 49.0), Adrenal (RPKM 44.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Slc45a4 in Genome Data Viewer
    Location:
    7q34
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (107370826..107459163, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (105478886..105550160, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (114817817..114888998, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L36 like 1 Neighboring gene DENN domain containing 3 Neighboring gene uncharacterized LOC134479924 Neighboring gene G protein-coupled receptor 20

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Proton-associated sucrose transport of mammalian solute carrier family 45: an analysis in Saccharomyces cerevisiae. Bartölke R, et al. Biochem J, 2014 Dec 1. PMID 25164149
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables sucrose:proton symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sucrose:proton symporter activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within sucrose transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    solute carrier family 45 member 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      107370826..107459163 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063264631.1 → XP_063120701.1  solute carrier family 45 member 4

      UniProtKB/TrEMBL
      A6HRV7, D4ADC6

    2. XM_039080226.2 → XP_038936154.1  solute carrier family 45 member 4

      UniProtKB/TrEMBL
      A6HRV7, D4ADC6
      Related
      ENSRNOP00000029754.6, ENSRNOT00000032620.8
      Conserved Domains (1) summary
      cl28910
      Location:53 → 275
      MFS; Major Facilitator Superfamily

    3. XM_006241741.5 → XP_006241803.1  solute carrier family 45 member 4

      See identical proteins and their annotated locations for XP_006241803.1

      UniProtKB/TrEMBL
      A6HRV7, D4ADC6
      Conserved Domains (1) summary
      cl28910
      Location:53 → 275
      MFS; Major Facilitator Superfamily

    4. XM_039080227.2 → XP_038936155.1  solute carrier family 45 member 4

      UniProtKB/TrEMBL
      A6HRV7, D4ADC6
      Conserved Domains (1) summary
      cl28910
      Location:53 → 275
      MFS; Major Facilitator Superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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