Rdh11 retinol dehydrogenase 11 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Rdh11provided by RGD
Official Full Name: retinol dehydrogenase 11provided by RGD
Primary source: RGD:1312001
See related: EnsemblRapid:ENSRNOG00000054770 AllianceGenome:RGD:1312001
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable aldehyde dehydrogenase (NADP+) activity and all-trans-retinol dehydrogenase (NADP+) activity. Predicted to be involved in cellular detoxification of aldehyde; retinol metabolic process; and visual perception. Predicted to act upstream of or within retinal metabolic process. Predicted to be located in endoplasmic reticulum membrane and photoreceptor inner segment. Orthologous to human RDH11 (retinol dehydrogenase 11). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Liver (RPKM 280.6), Testes (RPKM 275.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 6q24

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	6	NC_086024.1 (103712373..103728247, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	6	NC_051341.1 (97979377..97995252, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	6	NC_005105.4 (102356498..102372618, complement)

Chromosome 6 - NC_086024.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables aldehyde dehydrogenase (NADP+) activity	ISO Inferred from Sequence Orthology more info
enables all-trans-retinol dehydrogenase (NADP+) activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in cellular detoxification of aldehyde	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within retinal metabolic process	ISO Inferred from Sequence Orthology more info
involved_in retinoid metabolic process	ISO Inferred from Sequence Orthology more info
involved_in retinol metabolic process	ISO Inferred from Sequence Orthology more info
involved_in visual perception	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info
located_in photoreceptor inner segment	ISO Inferred from Sequence Orthology more info
NOT located_in photoreceptor outer segment membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: retinol dehydrogenase 11

Names: retinol dehydrogenase 11 (all-trans/9-cis/11-cis)

NP_001012193.1

EC 1.1.1.300

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.