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    Snx24 sorting nexin 24 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361328, updated on 9-Dec-2024

    Summary

    Official Symbol
    Snx24provided by RGD
    Official Full Name
    sorting nexin 24provided by RGD
    Primary source
    RGD:1306864
    See related
    EnsemblRapid:ENSRNOG00000017488 AllianceGenome:RGD:1306864
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable phosphatidylinositol-3-phosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylinositol-5-phosphate binding activity. Predicted to be involved in protein transport. Predicted to be located in cytoplasmic vesicle membrane. Orthologous to human SNX24 (sorting nexin 24). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 113.1), Kidney (RPKM 81.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Snx24 in Genome Data Viewer
    Location:
    18q11
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (48869804..49024352)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (46670987..46826070)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (48201653..48355701)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene aminomethyltransferase, pseudogene 1 Neighboring gene sorting nexin 2 Neighboring gene peptidylprolyl isomerase C Neighboring gene PR/SET domain 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC94664

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphatidylinositol-3-phosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables phosphatidylinositol-4-phosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables phosphatidylinositol-5-phosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    sorting nexin-24
    Names
    SBBI31 protein
    sorting nexing 24

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008364.1NP_001008365.1  sorting nexin-24

      See identical proteins and their annotated locations for NP_001008365.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085883
      UniProtKB/Swiss-Prot
      Q5U2S5
      UniProtKB/TrEMBL
      A0A8I6AQ57, A6IX29
      Related
      ENSRNOP00000023507.4, ENSRNOT00000023507.6
      Conserved Domains (1) summary
      cd06880
      Location:1111
      PX_SNX22; The phosphoinositide binding Phox Homology domain of Sorting Nexin 22

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      48869804..49024352
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063277476.1XP_063133546.1  sorting nexin-24 isoform X1

    2. XM_063277477.1XP_063133547.1  sorting nexin-24 isoform X2

    3. XM_063277478.1XP_063133548.1  sorting nexin-24 isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZMK1
      Related
      ENSRNOP00000109330.1, ENSRNOT00000147704.1
    4. XM_063277479.1XP_063133549.1  sorting nexin-24 isoform X4

    RNA

    1. XR_005496057.2 RNA Sequence