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    Fam118b family with sequence similarity 118, member B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315549, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fam118bprovided by RGD
    Official Full Name
    family with sequence similarity 118, member Bprovided by RGD
    Primary source
    RGD:1307173
    See related
    EnsemblRapid:ENSRNOG00000011543 AllianceGenome:RGD:1307173
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ppp4r1l; RGD1307173
    Summary
    Predicted to enable identical protein binding activity. Predicted to be located in Cajal body. Orthologous to human FAM118B (family with sequence similarity 118 member B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 118.6), Spleen (RPKM 92.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fam118b in Genome Data Viewer
    Location:
    8q21
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (41824522..41875190, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (33566681..33617310, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (36416769..36467609, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene FAD-dependent oxidoreductase domain containing 1 Neighboring gene TIR domain containing adaptor protein Neighboring gene SRP receptor subunit alpha Neighboring gene RNA pseudouridine synthase D4 Neighboring gene cell adhesion associated, oncogene regulated like 1 Neighboring gene cell adhesion associated, oncogene regulated

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC116168

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in Cajal body IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM118B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025283.2 → NP_001020454.1  protein FAM118B

      See identical proteins and their annotated locations for NP_001020454.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/Swiss-Prot
      Q4QQT2
      UniProtKB/TrEMBL
      A6JYK2
      Related
      ENSRNOP00000015366.6, ENSRNOT00000015366.9
      Conserved Domains (1) summary
      pfam13289
      Location:158 → 301
      SIR2_2; SIR2-like domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      41824522..41875190 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006242784.5 → XP_006242846.1  protein FAM118B isoform X1

      See identical proteins and their annotated locations for XP_006242846.1

      UniProtKB/Swiss-Prot
      Q4QQT2
      UniProtKB/TrEMBL
      A6JYK2
      Conserved Domains (1) summary
      pfam13289
      Location:158 → 301
      SIR2_2; SIR2-like domain

    2. XM_039081400.2 → XP_038937328.1  protein FAM118B isoform X1

      UniProtKB/Swiss-Prot
      Q4QQT2
      UniProtKB/TrEMBL
      A6JYK2
      Conserved Domains (1) summary
      pfam13289
      Location:158 → 301
      SIR2_2; SIR2-like domain

    3. XM_039081401.2 → XP_038937329.1  protein FAM118B isoform X2

      Conserved Domains (1) summary
      pfam13289
      Location:21 → 164
      SIR2_2; SIR2-like domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4QQT2.1 GenPept UniProtKB/Swiss-Prot:Q4QQT2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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