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    Ubtd2 ubiquitin domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287178, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ubtd2provided by RGD
    Official Full Name
    ubiquitin domain containing 2provided by RGD
    Primary source
    RGD:1305506
    See related
    EnsemblRapid:ENSRNOG00000004137 AllianceGenome:RGD:1305506
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305506
    Summary
    Orthologous to human UBTD2 (ubiquitin domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 74.9), Testes (RPKM 73.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ubtd2 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (17542008..17604548)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (17037716..17100263)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (17327250..17392431)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 134, pseudogene 1 Neighboring gene uncharacterized LOC120095060 Neighboring gene SH3 and PX domains 2B Neighboring gene EF-hand calcium binding domain 9 Neighboring gene serine/threonine kinase 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. miR-141-3p affects β-catenin signaling and apoptosis by targeting Ubtd2 in rats with anorectal malformations. Wang CY, et al. Ann N Y Acad Sci, 2022 Dec. PMID 36328940

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. miR-141-3p affects beta-catenin signaling and apoptosis by targeting Ubtd2 in rats with anorectal malformations.
      Title: miR-141-3p affects β-catenin signaling and apoptosis by targeting Ubtd2 in rats with anorectal malformations.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    ubiquitin domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001398573.1 → NP_001385502.1  ubiquitin domain-containing protein 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A8I5ZW20
      Related
      ENSRNOP00000084596.2, ENSRNOT00000115802.2
      Conserved Domains (2) summary
      cd17121
      Location:151 → 225
      Ubl_UBTD2; ubiquitin-like (Ubl) domain found in ubiquitin domain-containing protein 2 (UBTD2)
      pfam16455
      Location:30 → 132
      UBD; Ubiquitin-binding domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      17542008..17604548
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039087138.2 → XP_038943066.1  ubiquitin domain-containing protein 2 isoform X6

      Conserved Domains (1) summary
      pfam16455
      Location:30 → 103
      UBD; Ubiquitin-binding domain

    2. XM_039087136.2 → XP_038943064.1  ubiquitin domain-containing protein 2 isoform X4

      Conserved Domains (1) summary
      pfam16455
      Location:30 → 102
      UBD; Ubiquitin-binding domain

    3. XM_039087133.2 → XP_038943061.1  ubiquitin domain-containing protein 2 isoform X2

      Conserved Domains (2) summary
      cd17121
      Location:72 → 146
      Ubl_UBTD2; ubiquitin-like (Ubl) domain found in ubiquitin domain-containing protein 2 (UBTD2)
      pfam16455
      Location:24 → 53
      UBD; Ubiquitin-binding domain

    4. XM_039087132.2 → XP_038943060.1  ubiquitin domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A6HDF2
      Conserved Domains (2) summary
      cd17121
      Location:107 → 181
      Ubl_UBTD2; ubiquitin-like (Ubl) domain found in ubiquitin domain-containing protein 2 (UBTD2)
      pfam16455
      Location:1 → 88
      UBD; Ubiquitin-binding domain

    5. XM_017597618.3 → XP_017453107.1  ubiquitin domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A6HDF2
      Conserved Domains (2) summary
      cd17121
      Location:107 → 181
      Ubl_UBTD2; ubiquitin-like (Ubl) domain found in ubiquitin domain-containing protein 2 (UBTD2)
      pfam16455
      Location:1 → 88
      UBD; Ubiquitin-binding domain

    6. XM_039087134.1 → XP_038943062.1  ubiquitin domain-containing protein 2 isoform X3

      Conserved Domains (2) summary
      cd17121
      Location:71 → 145
      Ubl_UBTD2; ubiquitin-like (Ubl) domain found in ubiquitin domain-containing protein 2 (UBTD2)
      pfam16455
      Location:14 → 52
      UBD; Ubiquitin-binding domain

    7. XM_039087135.2 → XP_038943063.1  ubiquitin domain-containing protein 2 isoform X3

      Conserved Domains (2) summary
      cd17121
      Location:71 → 145
      Ubl_UBTD2; ubiquitin-like (Ubl) domain found in ubiquitin domain-containing protein 2 (UBTD2)
      pfam16455
      Location:14 → 52
      UBD; Ubiquitin-binding domain

    8. XM_039087137.2 → XP_038943065.1  ubiquitin domain-containing protein 2 isoform X5

      Conserved Domains (2) summary
      cd17121
      Location:51 → 125
      Ubl_UBTD2; ubiquitin-like (Ubl) domain found in ubiquitin domain-containing protein 2 (UBTD2)
      pfam16455
      Location:3 → 32
      UBD; Ubiquitin-binding domain
    Nucleotide Protein Strain
    Heading Accession and Version

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