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    Spats2l spermatogenesis associated, serine-rich 2-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316426, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Spats2lprovided by RGD
    Official Full Name
    spermatogenesis associated, serine-rich 2-likeprovided by RGD
    Primary source
    RGD:1309930
    See related
    EnsemblRapid:ENSRNOG00000016012 AllianceGenome:RGD:1309930
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309930
    Summary
    Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm. Orthologous to human SPATS2L (spermatogenesis associated serine rich 2 like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 60.9), Brain (RPKM 43.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Spats2l in Genome Data Viewer
    Location:
    9q31
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (66814217..66988084)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (59319949..59493864)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (64643223..64843963)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108351935 Neighboring gene ribosomal protein L6, pseudogene 7 Neighboring gene uncharacterized LOC120094689 Neighboring gene 60S ribosomal protein L30-like Neighboring gene U6 spliceosomal RNA Neighboring gene potassium channel tetramerization domain containing 18 Neighboring gene shugoshin 2 Neighboring gene aldehyde oxidase 1 Neighboring gene uncharacterized LOC120094690

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. FMRP recruitment of β-catenin to the translation pre-initiation complex represses translation. Ehyai S, et al. EMBO Rep, 2018 Dec. PMID 30361391, Free PMC Article
    2. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of protein-containing complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    SPATS2-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014102.1 → NP_001014124.1  SPATS2-like protein

      See identical proteins and their annotated locations for NP_001014124.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085874
      UniProtKB/Swiss-Prot
      Q5U2T3
      UniProtKB/TrEMBL
      A0A0G2JVT4, A6IP44
      Conserved Domains (1) summary
      pfam07139
      Location:59 → 368
      DUF1387; Protein of unknown function (DUF1387)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      66814217..66988084
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006244992.4 → XP_006245054.1  SPATS2-like protein isoform X6

      See identical proteins and their annotated locations for XP_006245054.1

      UniProtKB/TrEMBL
      A0A8I5Y6T6, A6IP42
      Conserved Domains (1) summary
      pfam07139
      Location:79 → 388
      DUF1387; Protein of unknown function (DUF1387)

    2. XM_006244990.5 → XP_006245052.2  SPATS2-like protein isoform X5

      UniProtKB/TrEMBL
      A0A0G2JVT4

    3. XM_063267193.1 → XP_063123263.1  SPATS2-like protein isoform X1

      UniProtKB/TrEMBL
      A0A0G2JVT4

    4. XM_063267194.1 → XP_063123264.1  SPATS2-like protein isoform X2

      UniProtKB/TrEMBL
      A0A0G2JVT4

    5. XM_063267195.1 → XP_063123265.1  SPATS2-like protein isoform X3

    6. XM_063267196.1 → XP_063123266.1  SPATS2-like protein isoform X4

    7. XM_017596460.3 → XP_017451949.1  SPATS2-like protein isoform X6

      UniProtKB/TrEMBL
      A0A8I5Y6T6, A6IP42
      Conserved Domains (1) summary
      pfam07139
      Location:79 → 388
      DUF1387; Protein of unknown function (DUF1387)

    8. XM_063267197.1 → XP_063123267.1  SPATS2-like protein isoform X6

      UniProtKB/TrEMBL
      A0A8I5Y6T6, A6IP42

    9. XM_063267201.1 → XP_063123271.1  SPATS2-like protein isoform X8

      UniProtKB/Swiss-Prot
      Q5U2T3
      UniProtKB/TrEMBL
      A0A0G2JVT4, A6IP44

    10. XM_039083628.2 → XP_038939556.1  SPATS2-like protein isoform X6

      UniProtKB/TrEMBL
      A0A8I5Y6T6, A6IP42
      Conserved Domains (1) summary
      pfam07139
      Location:79 → 388
      DUF1387; Protein of unknown function (DUF1387)

    11. XM_063267200.1 → XP_063123270.1  SPATS2-like protein isoform X8

      UniProtKB/Swiss-Prot
      Q5U2T3
      UniProtKB/TrEMBL
      A0A0G2JVT4, A6IP44

    12. XM_039083627.2 → XP_038939555.1  SPATS2-like protein isoform X6

      UniProtKB/TrEMBL
      A0A8I5Y6T6, A6IP42
      Conserved Domains (1) summary
      pfam07139
      Location:79 → 388
      DUF1387; Protein of unknown function (DUF1387)

    13. XM_063267198.1 → XP_063123268.1  SPATS2-like protein isoform X7

      UniProtKB/TrEMBL
      A0A8I5Y6T6, A0A8L2QB71
      Related
      ENSRNOP00000021527.6, ENSRNOT00000021527.8

    14. XM_039083630.2 → XP_038939558.1  SPATS2-like protein isoform X9

      UniProtKB/TrEMBL
      A0A8I5Y6T6, A0A8I5ZRR1, A6IP43
      Conserved Domains (1) summary
      pfam07139
      Location:79 → 319
      DUF1387; Protein of unknown function (DUF1387)

    15. XM_063267199.1 → XP_063123269.1  SPATS2-like protein isoform X10

      UniProtKB/TrEMBL
      A0A8I5Y6T6, A0A8I5Y992
      Related
      ENSRNOP00000077000.1, ENSRNOT00000100381.2

    16. XM_039083629.2 → XP_038939557.1  SPATS2-like protein isoform X8

      UniProtKB/Swiss-Prot
      Q5U2T3
      UniProtKB/TrEMBL
      A0A0G2JVT4, A6IP44
      Conserved Domains (1) summary
      pfam07139
      Location:59 → 368
      DUF1387; Protein of unknown function (DUF1387)

    17. XM_008767110.3 → XP_008765332.1  SPATS2-like protein isoform X8

      See identical proteins and their annotated locations for XP_008765332.1

      UniProtKB/Swiss-Prot
      Q5U2T3
      UniProtKB/TrEMBL
      A0A0G2JVT4, A6IP44
      Related
      ENSRNOP00000069610.2, ENSRNOT00000081497.3
      Conserved Domains (1) summary
      pfam07139
      Location:59 → 368
      DUF1387; Protein of unknown function (DUF1387)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5U2T3.1 GenPept UniProtKB/Swiss-Prot:Q5U2T3

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