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    Slc22a15 solute carrier family 22, member 15 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310732, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Slc22a15provided by RGD
    Official Full Name
    solute carrier family 22, member 15provided by RGD
    Primary source
    RGD:1311184
    See related
    EnsemblRapid:ENSRNOG00000033051 AllianceGenome:RGD:1311184
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable amino-acid betaine transmembrane transporter activity. Predicted to be involved in amino-acid betaine transport and transmembrane transport. Predicted to be located in plasma membrane. Orthologous to human SLC22A15 (solute carrier family 22 member 15). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 40.6), Brain (RPKM 20.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Slc22a15 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (191987409..192049859, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (189298836..189359902, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (204281638..204344026, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103691652 Neighboring gene mab-21 like 3 Neighboring gene nescient helix loop helix 2 Neighboring gene DnaJ heat shock protein family (Hsp40) member B6, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables amino-acid betaine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino-acid betaine transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    solute carrier family 22 member 15
    Names
    solute carrier family 22 (organic cation transporter), member 15

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107707.2 → NP_001101177.1  solute carrier family 22 member 15

      See identical proteins and their annotated locations for NP_001101177.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A6K3I1, D4A271
      Related
      ENSRNOP00000021713.5, ENSRNOT00000021713.7
      Conserved Domains (1) summary
      cd17377
      Location:71 → 469
      MFS_SLC22A15; Solute carrier family 22 member 15 of the Major Facilitator Superfamily of transporters

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      191987409..192049859 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017590914.3 → XP_017446403.1  solute carrier family 22 member 15 isoform X1

    2. XM_039102400.1 → XP_038958328.1  solute carrier family 22 member 15 isoform X2

      Conserved Domains (1) summary
      cl28910
      Location:60 → 226
      MFS; Major Facilitator Superfamily

    3. XM_039102401.2 → XP_038958329.1  solute carrier family 22 member 15 isoform X3

      Conserved Domains (1) summary
      cl28910
      Location:71 → 244
      MFS; Major Facilitator Superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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