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    Bphl biphenyl hydrolase like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361239, updated on 9-Dec-2024

    Summary

    Official Symbol
    Bphlprovided by RGD
    Official Full Name
    biphenyl hydrolase likeprovided by RGD
    Primary source
    RGD:1307572
    See related
    EnsemblRapid:ENSRNOG00000017577 AllianceGenome:RGD:1307572
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable alpha-amino-acid esterase activity and poly(ADP-ribose) glycohydrolase activity. Predicted to be involved in ATP generation from poly-ADP-D-ribose. Predicted to be located in cytosol; mitochondrion; and nuclear body. Orthologous to human BPHL (biphenyl hydrolase like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 355.4), Liver (RPKM 179.6) and 5 other tissues See more
    Orthologs
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    Genomic context

    See Bphl in Genome Data Viewer
    Location:
    17p12
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (31006283..31042631, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (30800939..30837277, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (31498877..31535172, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene tubulin, beta 2A class IIa like 1 Neighboring gene tubulin, beta 2A class IIa Neighboring gene receptor interacting serine/threonine kinase 1 Neighboring gene serpin family B member 6A Neighboring gene N-ribosyldihydronicotinamide:quinone dehydrogenase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • MGC125077

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in cytosol  
    located_in mitochondrion  
    located_in nuclear body  
    located_in nucleoplasm  
    located_in nucleus  

    General protein information

    Preferred Names
    valacyclovir hydrolase
    Names
    biphenyl hydrolase-like (serine hydrolase)
    biphenyl hydrolase-like (serine hydrolase, breast epithelial mucin-associated antigen)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037206.1NP_001032283.1  valacyclovir hydrolase

      See identical proteins and their annotated locations for NP_001032283.1

      Status: PROVISIONAL

      Source sequence(s)
      BC105908
      UniProtKB/TrEMBL
      F7FBS0, Q3B8N9
      Related
      ENSRNOP00000023914.6, ENSRNOT00000023914.8
      Conserved Domains (1) summary
      COG0596
      Location:44291
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      31006283..31042631 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063276588.1XP_063132658.1  valacyclovir hydrolase isoform X4

    2. XM_063276586.1XP_063132656.1  valacyclovir hydrolase isoform X1

    3. XM_039095883.1XP_038951811.1  valacyclovir hydrolase isoform X3

      UniProtKB/TrEMBL
      A6J7G9
      Conserved Domains (1) summary
      COG0596
      Location:25189
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
    4. XM_063276587.1XP_063132657.1  valacyclovir hydrolase isoform X2

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