U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Raet1e retinoic acid early transcript 1E [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292450, updated on 4-Jan-2025

    Summary

    Go to the top of the page Help
    Symbol
    Raet1eprovided by RGD
    Full Name
    retinoic acid early transcript 1Eprovided by RGD
    Primary source
    RGD:1311118
    See related
    AllianceGenome:RGD:1311118
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable natural killer cell lectin-like receptor binding activity. Predicted to be involved in natural killer cell mediated cytotoxicity and positive regulation of natural killer cell mediated cytotoxicity. Predicted to act upstream of or within T cell mediated cytotoxicity. Orthologous to human RAET1E (retinoic acid early transcript 1E). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Spleen (RPKM 16.6), Muscle (RPKM 13.7) and 7 other tissues See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Raet1e in Genome Data Viewer
    Location:
    1p13
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (3474487..3476431, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (1662665..1664609, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (1101666..1120340, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene vomeronasal 2, receptor 116 like, pseudogene 17 Neighboring gene retinoic acid early-inducible protein 1-gamma-like Neighboring gene UL16 binding protein 1 Neighboring gene histocompatibility 60b like 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D. Bacon L, et al. J Immunol, 2004 Jul 15. PMID 15240696
    2. Four novel ULBP splice variants are ligands for human NKG2D. Cao W, et al. Int Immunol, 2008 Aug. PMID 18544572
    3. Regulation of cutaneous malignancy by gammadelta T cells. Girardi M, et al. Science, 2001 Oct 19. PMID 11567106
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables natural killer cell lectin-like receptor binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within T cell mediated cytotoxicity ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in natural killer cell mediated cytotoxicity ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of natural killer cell mediated cytotoxicity ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    retinoic acid early transcript 1E; retinoic acid early-inducible protein 1-beta
    Names
    retinoic acid early-inducible protein 1-gamma

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      3474487..3476431 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006227600.4 → XP_006227662.2  retinoic acid early-inducible protein 1-beta

      Conserved Domains (1) summary
      cl08246
      Location:20 → 188
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.