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    Akap14 A-kinase anchoring protein 14 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 60332, updated on 9-Dec-2024

    Summary

    Official Symbol
    Akap14provided by RGD
    Official Full Name
    A-kinase anchoring protein 14provided by RGD
    Primary source
    RGD:708510
    See related
    EnsemblRapid:ENSRNOG00000006899 AllianceGenome:RGD:708510
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables protein kinase A binding activity. Involved in spermatogenesis. Located in sperm fibrous sheath. Orthologous to human AKAP14 (A-kinase anchoring protein 14). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 22.8), Lung (RPKM 8.5) and 3 other tissues See more
    Orthologs
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    Genomic context

    See Akap14 in Genome Data Viewer
    Location:
    Xq35
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (121261195..121276376, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (116395512..116410697, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (123773430..123788898, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene UPF3B, regulator of nonsense mediated mRNA decay Neighboring gene NFKB activating protein Neighboring gene uncharacterized LOC134484097 Neighboring gene NADH:ubiquinone oxidoreductase subunit A1 Neighboring gene ring finger protein 113A1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in axoneme  
    part_of cAMP-dependent protein kinase complex  
    part_of cAMP-dependent protein kinase complex  
    located_in sperm fibrous sheath PubMed 

    General protein information

    Preferred Names
    A-kinase anchor protein 14
    Names
    A kinase (PRKA) anchor protein 14
    AKAP-14
    TAKAP-1.2
    Testis-specific A-kinase-anchoring-protein
    testis-specific A-kinase-anchoring protein TAKAP-80

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021703.1NP_067735.1  A-kinase anchor protein 14

      See identical proteins and their annotated locations for NP_067735.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ002474
      UniProtKB/Swiss-Prot
      O35817
      UniProtKB/TrEMBL
      A0A8I6ANA3, A6JMH8
      Related
      ENSRNOP00000009123.2, ENSRNOT00000009123.7
      Conserved Domains (1) summary
      pfam14469
      Location:374494
      AKAP28; 28 kDa A-kinase anchor

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      121261195..121276376 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039100002.2XP_038955930.1  A-kinase anchor protein 14 isoform X1

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