Ctnnbl1 catenin, beta like 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ctnnbl1provided by RGD
Official Full Name: catenin, beta like 1provided by RGD
Primary source: RGD:1563558
See related: EnsemblRapid:ENSRNOG00000012021 AllianceGenome:RGD:1563558
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable enzyme binding activity. Predicted to be involved in positive regulation of apoptotic process and somatic diversification of immunoglobulins. Predicted to be located in centrosome; cytosol; and nucleoplasm. Predicted to be part of Prp19 complex and spliceosomal complex. Human ortholog(s) of this gene implicated in colorectal cancer; morbid obesity; and primary immunodeficiency disease. Orthologous to human CTNNBL1 (catenin beta like 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 166.0), Adrenal (RPKM 118.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 3q42

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (166807899..166968932)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (146387940..146548987)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (154212245..154373170)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

Brp44l (e-PCR), detects polymorphism
- UniSTS:226033

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables enzyme binding	IEA Inferred from Electronic Annotation more info
enables enzyme binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in RNA splicing	IEA Inferred from Electronic Annotation more info
involved_in adaptive immune response	IEA Inferred from Electronic Annotation more info
involved_in biological_process	ND No biological Data available more info
involved_in mRNA processing	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of apoptotic process	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in somatic diversification of immunoglobulins	IEA Inferred from Electronic Annotation more info
involved_in somatic diversification of immunoglobulins	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of Prp19 complex	IEA Inferred from Electronic Annotation more info
part_of Prp19 complex	ISO Inferred from Sequence Orthology more info
part_of Prp19 complex	ISS Inferred from Sequence or Structural Similarity more info
located_in centrosome	IEA Inferred from Electronic Annotation more info
located_in centrosome	ISO Inferred from Sequence Orthology more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info
part_of spliceosomal complex	IBA Inferred from Biological aspect of Ancestor more info
part_of spliceosomal complex	IEA Inferred from Electronic Annotation more info
part_of spliceosomal complex	ISO Inferred from Sequence Orthology more info
part_of spliceosomal complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: beta-catenin-like protein 1

Names: NAP; beta catenin-like 1; nuclear-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.