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    Tmem248 transmembrane protein 248 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288616, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmem248provided by RGD
    Official Full Name
    transmembrane protein 248provided by RGD
    Primary source
    RGD:1303319
    See related
    EnsemblRapid:ENSRNOG00000000893 AllianceGenome:RGD:1303319
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in membrane. Orthologous to human TMEM248 (transmembrane protein 248). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 109.2), Muscle (RPKM 99.9) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Tmem248 in Genome Data Viewer
    Location:
    12q12
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (32069113..32093380, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (26430775..26457105, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (29931728..29958050, complement)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene tRNA-yW synthesizing protein 1 homolog Neighboring gene interferon induced transmembrane protein 1, pseudogene 2 Neighboring gene Sbds, ribosome maturation factor Neighboring gene transfer RNA leucine (anticodon AAG) 19 Neighboring gene RAB guanine nucleotide exchange factor 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • MGC94190

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane  

    General protein information

    Preferred Names
    transmembrane protein 248
    Names
    UPF0458 protein C7orf42 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004204.2NP_001004204.1  transmembrane protein 248

      See identical proteins and their annotated locations for NP_001004204.1

      Status: PROVISIONAL

      Source sequence(s)
      BC090318
      UniProtKB/Swiss-Prot
      Q6AY76
      UniProtKB/TrEMBL
      A0A8L2R2J4, A6J0M4
      Conserved Domains (1) summary
      pfam14940
      Location:10257
      TMEM219; Transmembrane 219

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      32069113..32093380 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063271161.1XP_063127231.1  transmembrane protein 248 isoform X1

      UniProtKB/Swiss-Prot
      Q6AY76
      UniProtKB/TrEMBL
      A0A8L2R2J4, A6J0M4
    2. XM_063271162.1XP_063127232.1  transmembrane protein 248 isoform X1

      UniProtKB/Swiss-Prot
      Q6AY76
      UniProtKB/TrEMBL
      A0A8L2R2J4, A6J0M4
    3. XM_063271160.1XP_063127230.1  transmembrane protein 248 isoform X1

      UniProtKB/Swiss-Prot
      Q6AY76
      UniProtKB/TrEMBL
      A0A8L2R2J4, A6J0M4
      Related
      ENSRNOP00000055516.1, ENSRNOT00000058725.4
    4. XM_006249230.5XP_006249292.1  transmembrane protein 248 isoform X1

      See identical proteins and their annotated locations for XP_006249292.1

      UniProtKB/Swiss-Prot
      Q6AY76
      UniProtKB/TrEMBL
      A0A8L2R2J4, A6J0M4
      Conserved Domains (1) summary
      pfam14940
      Location:10257
      TMEM219; Transmembrane 219
    5. XM_063271163.1XP_063127233.1  transmembrane protein 248 isoform X1

      UniProtKB/Swiss-Prot
      Q6AY76
      UniProtKB/TrEMBL
      A0A8L2R2J4, A6J0M4
      Related
      ENSRNOP00000070412.2, ENSRNOT00000086175.3
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