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    Slc25a38 solute carrier family 25, member 38 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 301067, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slc25a38provided by RGD
    Official Full Name
    solute carrier family 25, member 38provided by RGD
    Primary source
    RGD:1311914
    See related
    EnsemblRapid:ENSRNOG00000018552 AllianceGenome:RGD:1311914
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311914
    Summary
    Predicted to enable glycine transmembrane transporter activity. Predicted to be involved in erythrocyte differentiation and glycine import into mitochondrion. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in autosomal recessive pyridoxine-refractory sideroblastic anemia 2. Orthologous to human SLC25A38 (solute carrier family 25 member 38). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 83.3), Spleen (RPKM 57.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Slc25a38 in Genome Data Viewer
    Location:
    8q32
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (128713180..128725968)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (119835546..119848334)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (128790348..128802988)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134480114 Neighboring gene C-X3-C motif chemokine receptor 1 Neighboring gene C-C motif chemokine receptor 8 Neighboring gene small nucleolar RNA, H/ACA box 73B like 1 Neighboring gene small nucleolar RNA, H/ACA box 6 Neighboring gene ribosomal protein SA

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • MGC124671

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in erythrocyte differentiation  
    involved_in erythrocyte differentiation  
    involved_in erythrocyte differentiation  
    involved_in glycine import into mitochondrion  
    involved_in glycine import into mitochondrion  
    involved_in glycine import into mitochondrion  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane  
    located_in mitochondrial inner membrane  
    located_in mitochondrial inner membrane  
    is_active_in mitochondrion  
    located_in mitochondrion PubMed 

    General protein information

    Preferred Names
    mitochondrial glycine transporter

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030032.2NP_001025203.2  mitochondrial glycine transporter

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/Swiss-Prot
      G3V8E7, Q499U1
      UniProtKB/TrEMBL
      A0A8L2QD79
      Related
      ENSRNOP00000025142.6, ENSRNOT00000025142.8
      Conserved Domains (1) summary
      pfam00153
      Location:46137
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      128713180..128725968
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039081302.2XP_038937230.1  mitochondrial glycine transporter isoform X2

      Conserved Domains (1) summary
      pfam00153
      Location:51134
      Mito_carr; Mitochondrial carrier protein
    2. XM_006244089.5XP_006244151.1  mitochondrial glycine transporter isoform X1

      UniProtKB/TrEMBL
      A0A0G2K0U7, A0A8L2QD79
      Related
      ENSRNOP00000071588.1, ENSRNOT00000083329.3
      Conserved Domains (2) summary
      PTZ00169
      Location:30297
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:25116
      Mito_carr; Mitochondrial carrier protein
    3. XM_039081301.2XP_038937229.1  mitochondrial glycine transporter isoform X2

      Conserved Domains (1) summary
      pfam00153
      Location:51134
      Mito_carr; Mitochondrial carrier protein
    4. XM_039081304.2XP_038937232.1  mitochondrial glycine transporter isoform X3

      UniProtKB/TrEMBL
      A6I3Z2
      Conserved Domains (1) summary
      pfam00153
      Location:89176
      Mito_carr; Mitochondrial carrier protein
    5. XM_039081305.2XP_038937233.1  mitochondrial glycine transporter isoform X3

      UniProtKB/TrEMBL
      A6I3Z2
      Conserved Domains (1) summary
      pfam00153
      Location:89176
      Mito_carr; Mitochondrial carrier protein
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