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    Gp5 glycoprotein V (platelet) [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25259, updated on 9-Dec-2024

    Summary

    Symbol
    Gp5provided by RGD
    Full Name
    glycoprotein V (platelet)provided by RGD
    Primary source
    RGD:2724
    See related
    EnsemblRapid:ENSRNOG00000038540 AllianceGenome:RGD:2724
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    PLGPV
    Summary
    Predicted to enable collagen binding activity. Predicted to be involved in several processes, including blood coagulation, intrinsic pathway; megakaryocyte development; and positive regulation of platelet activation. Predicted to act upstream of or within cell-matrix adhesion and negative regulation of platelet activation. Located in cell surface. Orthologous to human GP5 (glycoprotein V platelet). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 41.8), Brain (RPKM 10.1) and 3 other tissues See more
    Orthologs
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    Genomic context

    See Gp5 in Genome Data Viewer
    Location:
    11q22
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (83948507..83952362)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (70443613..70446705)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (73015380..73017570)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095683 Neighboring gene ribosomal protein S26, pseudogene 13 Neighboring gene ATPase 13A3 Neighboring gene leucine rich repeat containing 15 Neighboring gene carboxypeptidase N subunit 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in cell surface PubMed 
    part_of glycoprotein Ib-IX-V complex  
    part_of glycoprotein Ib-IX-V complex  

    General protein information

    Preferred Names
    platelet glycoprotein V
    Names
    GPV
    Platelet glycoprotein 5
    Platelete glycoprotein 5
    glycoprotein 5, platelet

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012795.3NP_036927.2  platelet glycoprotein V precursor

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/Swiss-Prot
      O08770
      UniProtKB/TrEMBL
      A6JRV1, G3V9H9
      Related
      ENSRNOP00000047810.2, ENSRNOT00000040884.4
      Conserved Domains (4) summary
      PRK15370
      Location:103422
      PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
      TIGR00864
      Location:394458
      PCC; polycystin cation channel protein
      sd00033
      Location:100123
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:64110
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      83948507..83952362
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063270306.1XP_063126376.1  platelet glycoprotein V isoform X1

      UniProtKB/Swiss-Prot
      O08770
      UniProtKB/TrEMBL
      A6JRV1, G3V9H9
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