U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Fundc1 FUN14 domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363442, updated on 9-Dec-2024

    Summary

    Symbol
    Fundc1provided by RGD
    Full Name
    FUN14 domain containing 1provided by RGD
    Primary source
    RGD:1563372
    See related
    EnsemblRapid:ENSRNOG00000003470 AllianceGenome:RGD:1563372
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in mitochondrial fusion; mitophagy; and response to hypoxia. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial outer membrane. Orthologous to human FUNDC1 (FUN14 domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 195.3), Thymus (RPKM 140.8) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Fundc1 in Genome Data Viewer
    Location:
    Xq11
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (7666787..7683443)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (5083635..5100293)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (5549468..5566125)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene collagen alpha-1(VII) chain-like Neighboring gene collagen alpha-1(VII) chain-like Neighboring gene ADP-ribosylation factor-like 2, pseudogene 3 Neighboring gene ferritin light chain 1 pseudogene Neighboring gene uncharacterized LOC120099197 Neighboring gene proteasome 20S subunit alpha 2, pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    General gene information

    Clone Names

    • MGC109382

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in autophagy  
    involved_in autophagy of mitochondrion  
    acts_upstream_of_or_within autophagy of mitochondrion  
    involved_in autophagy of mitochondrion  
    involved_in autophagy of mitochondrion  
    involved_in mitochondrial fusion  
    involved_in mitophagy  
    acts_upstream_of_or_within response to hypoxia  
    involved_in response to hypoxia  
    involved_in response to hypoxia  
    Component Evidence Code Pubs
    is_active_in mitochondrial outer membrane  
    located_in mitochondrial outer membrane  
    located_in mitochondrial outer membrane  
    located_in mitochondrial outer membrane  
    located_in mitochondrion PubMed 

    General protein information

    Preferred Names
    FUN14 domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025027.1NP_001020198.1  FUN14 domain-containing protein 1

      See identical proteins and their annotated locations for NP_001020198.1

      Status: PROVISIONAL

      Source sequence(s)
      BC091353
      UniProtKB/Swiss-Prot
      Q5BJS4
      UniProtKB/TrEMBL
      A6JZV7
      Related
      ENSRNOP00000004676.5, ENSRNOT00000004676.8
      Conserved Domains (1) summary
      pfam04930
      Location:54153
      FUN14; FUN14 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      7666787..7683443
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    External link. Please review our privacy policy.