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    Ankrd22 ankyrin repeat domain 22 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 294093, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ankrd22provided by RGD
    Official Full Name
    ankyrin repeat domain 22provided by RGD
    Primary source
    RGD:1307862
    See related
    EnsemblRapid:ENSRNOG00000019190 AllianceGenome:RGD:1307862
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in membrane. Orthologous to human ANKRD22 (ankyrin repeat domain 22). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 25.9), Uterus (RPKM 5.4) and 3 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ankrd22 in Genome Data Viewer
    Location:
    1q52
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (241052235..241083737, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (231639035..231670537, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (252430750..252461346, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene lipase, family member N Neighboring gene lipase, family member M Neighboring gene STAM binding protein-like 1 Neighboring gene actin alpha 2, smooth muscle

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat domain-containing protein 22

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191638.1 → NP_001178567.1  ankyrin repeat domain-containing protein 22

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I6A2D2, D4ADM7
      Related
      ENSRNOP00000026093.3, ENSRNOT00000026093.7
      Conserved Domains (4) summary
      cd00204
      Location:39 → 187
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:44 → 165
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:5 → 60
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:39 → 70
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      241052235..241083737 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039109292.2 → XP_038965220.1  ankyrin repeat domain-containing protein 22 isoform X1

      Conserved Domains (2) summary
      sd00045
      Location:39 → 70
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:9 → 103
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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