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    Atf7ip2 activating transcription factor 7 interacting protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 497859, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Atf7ip2provided by RGD
    Official Full Name
    activating transcription factor 7 interacting protein 2provided by RGD
    Primary source
    RGD:1583744
    See related
    EnsemblRapid:ENSRNOG00000025522 AllianceGenome:RGD:1583744
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Orthologous to human ATF7IP2 (activating transcription factor 7 interacting protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 23.4), Kidney (RPKM 3.9) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Atf7ip2 in Genome Data Viewer
    Location:
    10q11
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (5909898..5952844, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (5403099..5445989, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (5476205..5519893, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene tektin 5 Neighboring gene epithelial membrane protein 2 Neighboring gene uncharacterized LOC134480748 Neighboring gene ribosomal protein L39 like 1 Neighboring gene uncharacterized LOC108352053

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The novel testicular enrichment protein Cfap58 is required for Notch-associated ciliogenesis. Li ZZ, et al. Biosci Rep, 2020 Jan 31. PMID 31904090, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    activating transcription factor 7-interacting protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017471.1 → NP_001017471.1  activating transcription factor 7-interacting protein 2

      See identical proteins and their annotated locations for NP_001017471.1

      Status: PROVISIONAL

      Source sequence(s)
      BC083663
      UniProtKB/TrEMBL
      Q5XIL7
      Related
      ENSRNOP00000032259.5, ENSRNOT00000039429.6
      Conserved Domains (1) summary
      pfam16788
      Location:59 → 262
      ATF7IP_BD; ATF-interacting protein binding domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      5909898..5952844 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008767495.4 → XP_008765717.1  activating transcription factor 7-interacting protein 2 isoform X3

      UniProtKB/TrEMBL
      F7EMW9
      Conserved Domains (1) summary
      pfam16788
      Location:70 → 273
      ATF7IP_BD; ATF-interacting protein binding domain

    2. XM_006245728.5 → XP_006245790.1  activating transcription factor 7-interacting protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZM83
      Related
      ENSRNOP00000079052.1, ENSRNOT00000109058.2
      Conserved Domains (2) summary
      pfam16788
      Location:70 → 273
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:353 → 451
      fn3_4; Fibronectin-III type domain

    3. XM_006245732.5 → XP_006245794.1  activating transcription factor 7-interacting protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZXG6
      Conserved Domains (2) summary
      pfam16788
      Location:59 → 262
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:342 → 440
      fn3_4; Fibronectin-III type domain

    4. XM_008767496.4 → XP_008765718.1  activating transcription factor 7-interacting protein 2 isoform X4

      UniProtKB/TrEMBL
      A6K4K8
      Conserved Domains (1) summary
      pfam16788
      Location:70 → 273
      ATF7IP_BD; ATF-interacting protein binding domain

    RNA

    1. XR_005489903.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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