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    Aldh16a1 aldehyde dehydrogenase 16 family, member A1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361571, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Aldh16a1provided by RGD
    Official Full Name
    aldehyde dehydrogenase 16 family, member A1provided by RGD
    Primary source
    RGD:1566295
    See related
    EnsemblRapid:ENSRNOG00000020623 AllianceGenome:RGD:1566295
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable aldehyde dehydrogenase (NAD+) activity. Orthologous to human ALDH16A1 (aldehyde dehydrogenase 16 family member A1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 271.5), Spleen (RPKM 179.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Aldh16a1 in Genome Data Viewer
    Location:
    1q22
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (104763200..104776270, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (95626727..95639808, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (101138237..101151320, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA Z195/SNORD33/SNORD32 family Neighboring gene ribosomal protein L13A Neighboring gene Fms related receptor tyrosine kinase 3 ligand Neighboring gene PIH1 domain containing 1 Neighboring gene solute carrier family 17 member 7 Neighboring gene golgi-associated, olfactory signaling regulator

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
    2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC124726

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables aldehyde dehydrogenase (NAD+) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    aldehyde dehydrogenase family 16 member A1
    Names
    aldehyde dehydrogenase 16A1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033706.1 → NP_001028878.1  aldehyde dehydrogenase family 16 member A1

      See identical proteins and their annotated locations for NP_001028878.1

      Status: PROVISIONAL

      Source sequence(s)
      BC101860
      UniProtKB/Swiss-Prot
      Q3T1L0
      UniProtKB/TrEMBL
      A6JAY6
      Related
      ENSRNOP00000087100.1, ENSRNOT00000109143.2
      Conserved Domains (1) summary
      cl11961
      Location:19 → 491
      ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      104763200..104776270 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006229100.3 → XP_006229162.1  aldehyde dehydrogenase family 16 member A1 isoform X1

      UniProtKB/TrEMBL
      A0A8I6GLW4, A0A8L2QFC7
      Related
      ENSRNOP00000027992.5, ENSRNOT00000027992.9
      Conserved Domains (1) summary
      cl11961
      Location:3 → 430
      ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily

    2. XM_039082201.2 → XP_038938129.1  aldehyde dehydrogenase family 16 member A1 isoform X2

      Conserved Domains (1) summary
      cl11961
      Location:1 → 310
      ALDH-SF; NAD(P)+-dependent aldehyde dehydrogenase superfamily
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3T1L0.1 GenPept UniProtKB/Swiss-Prot:Q3T1L0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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