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    Ankrd46 ankyrin repeat domain 46 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 299982, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ankrd46provided by RGD
    Official Full Name
    ankyrin repeat domain 46provided by RGD
    Primary source
    RGD:1309382
    See related
    EnsemblRapid:ENSRNOG00000025504 AllianceGenome:RGD:1309382
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    ank-s; RGD1309382
    Summary
    Predicted to be located in membrane. Orthologous to human ANKRD46 (ankyrin repeat domain 46). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 248.6), Kidney (RPKM 150.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ankrd46 in Genome Data Viewer
    Location:
    7q22
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (69532303..69553311, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (67647202..67668180, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (75279443..75300442, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479894 Neighboring gene uncharacterized LOC134479711 Neighboring gene uncharacterized LOC134479895 Neighboring gene sorting nexin 31 Neighboring gene poly(A) binding protein, cytoplasmic 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, et al. J Proteome Res, 2012 Sep 7. PMID 22871113, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC124899

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat domain-containing protein 46
    Names
    ankyrin repeat small protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013948.2 → NP_001013970.1  ankyrin repeat domain-containing protein 46

      See identical proteins and their annotated locations for NP_001013970.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/Swiss-Prot
      Q0VGK7, Q76K24
      UniProtKB/TrEMBL
      A0A8I5YBV2, A6HR28
      Conserved Domains (3) summary
      sd00045
      Location:15 → 42
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:16 → 103
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:82 → 142
      Ank_2; Ankyrin repeats (3 copies)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      69532303..69553311 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006241531.5 → XP_006241593.1  ankyrin repeat domain-containing protein 46 isoform X1

      See identical proteins and their annotated locations for XP_006241593.1

      UniProtKB/Swiss-Prot
      Q0VGK7, Q76K24
      UniProtKB/TrEMBL
      A0A8I5YBV2, A6HR28
      Related
      ENSRNOP00000034048.5, ENSRNOT00000036904.7
      Conserved Domains (3) summary
      sd00045
      Location:15 → 42
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:16 → 103
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:82 → 142
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_006241530.5 → XP_006241592.1  ankyrin repeat domain-containing protein 46 isoform X1

      See identical proteins and their annotated locations for XP_006241592.1

      UniProtKB/Swiss-Prot
      Q0VGK7, Q76K24
      UniProtKB/TrEMBL
      A0A8I5YBV2, A6HR28
      Conserved Domains (3) summary
      sd00045
      Location:15 → 42
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:16 → 103
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:82 → 142
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_063263262.1 → XP_063119332.1  ankyrin repeat domain-containing protein 46 isoform X1

      UniProtKB/Swiss-Prot
      Q0VGK7, Q76K24
      UniProtKB/TrEMBL
      A0A8I5YBV2, A6HR28

    4. XM_006241532.5 → XP_006241594.1  ankyrin repeat domain-containing protein 46 isoform X1

      See identical proteins and their annotated locations for XP_006241594.1

      UniProtKB/Swiss-Prot
      Q0VGK7, Q76K24
      UniProtKB/TrEMBL
      A0A8I5YBV2, A6HR28
      Conserved Domains (3) summary
      sd00045
      Location:15 → 42
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:16 → 103
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:82 → 142
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q76K24.1 GenPept UniProtKB/Swiss-Prot:Q76K24

    Gene LinkOut

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