Micall1 MICAL-like 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Micall1provided by RGD
Official Full Name: MICAL-like 1provided by RGD
Primary source: RGD:1305415
See related: EnsemblRapid:ENSRNOG00000026212 AllianceGenome:RGD:1305415
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1305415
Summary: Predicted to enable identical protein binding activity; phosphatidic acid binding activity; and small GTPase binding activity. Involved in cellular response to nerve growth factor stimulus; neuron projection development; and protein localization to endosome. Located in endosome membrane. Orthologous to human MICALL1 (MICAL like 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Heart (RPKM 75.4), Testes (RPKM 46.5) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 7q34

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (112557192..112587618)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (110676706..110707171)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (120343900..120375151)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables identical protein binding	IEA Inferred from Electronic Annotation more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables phosphatidic acid binding	IEA Inferred from Electronic Annotation more info
enables phosphatidic acid binding	ISO Inferred from Sequence Orthology more info
enables phosphatidic acid binding	ISS Inferred from Sequence or Structural Similarity more info
enables small GTPase binding	IEA Inferred from Electronic Annotation more info
enables small GTPase binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cellular response to nerve growth factor stimulus	IDA Inferred from Direct Assay more info	PubMed
involved_in endocytic recycling	ISO Inferred from Sequence Orthology more info
involved_in endocytic recycling	ISS Inferred from Sequence or Structural Similarity more info
involved_in endocytosis	ISO Inferred from Sequence Orthology more info
involved_in endocytosis	ISS Inferred from Sequence or Structural Similarity more info
involved_in neuron projection development	IEA Inferred from Electronic Annotation more info
involved_in neuron projection development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in neuron projection development	ISO Inferred from Sequence Orthology more info
involved_in plasma membrane tubulation	IEA Inferred from Electronic Annotation more info
involved_in plasma membrane tubulation	ISO Inferred from Sequence Orthology more info
involved_in plasma membrane tubulation	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein localization to endosome	IEA Inferred from Electronic Annotation more info
involved_in protein localization to endosome	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein localization to endosome	ISO Inferred from Sequence Orthology more info
involved_in protein targeting to membrane	IEA Inferred from Electronic Annotation more info
involved_in protein targeting to membrane	ISO Inferred from Sequence Orthology more info
involved_in protein targeting to membrane	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in receptor-mediated endocytosis	IEA Inferred from Electronic Annotation more info
involved_in receptor-mediated endocytosis	ISO Inferred from Sequence Orthology more info
involved_in receptor-mediated endocytosis	ISS Inferred from Sequence or Structural Similarity more info
involved_in slow endocytic recycling	IEA Inferred from Electronic Annotation more info
involved_in slow endocytic recycling	ISO Inferred from Sequence Orthology more info
involved_in slow endocytic recycling	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasmic side of endosome membrane	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic side of endosome membrane	ISO Inferred from Sequence Orthology more info
located_in cytoplasmic side of endosome membrane	ISS Inferred from Sequence or Structural Similarity more info
NOT located_in early endosome	ISO Inferred from Sequence Orthology more info
located_in endosome membrane	IDA Inferred from Direct Assay more info	PubMed
located_in late endosome	IEA Inferred from Electronic Annotation more info
located_in late endosome	ISO Inferred from Sequence Orthology more info
located_in late endosome	ISS Inferred from Sequence or Structural Similarity more info
located_in late endosome membrane	IEA Inferred from Electronic Annotation more info
located_in recycling endosome membrane	IEA Inferred from Electronic Annotation more info
NOT located_in recycling endosome membrane	ISO Inferred from Sequence Orthology more info
located_in recycling endosome membrane	ISO Inferred from Sequence Orthology more info
located_in recycling endosome membrane	ISS Inferred from Sequence or Structural Similarity more info
NOT located_in trans-Golgi network	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: MICAL-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.