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    Zfp772 zinc finger protein 772 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308318, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp772provided by RGD
    Official Full Name
    zinc finger protein 772provided by RGD
    Primary source
    RGD:1308782
    See related
    EnsemblRapid:ENSRNOG00000015598 AllianceGenome:RGD:1308782
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Zfp978; RGD1308782
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF773 (zinc finger protein 773). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 14.2), Lung (RPKM 13.4) and 9 other tissues See more
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    Genomic context

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    See Zfp772 in Genome Data Viewer
    Location:
    1q12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (75735754..75742480, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (66702628..66709355, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (69736905..69743906, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 418 like 1 Neighboring gene vomeronasal 1 receptor pseudogene 42 Neighboring gene hippocampus abundant gene transcript 1, pseudogene 1 Neighboring gene zinc finger protein 773, pseudogene 1 Neighboring gene uncharacterized LOC108349540

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC114396

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 419
    Names
    zinc finger protein 978

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025677.2 → NP_001020848.1  zinc finger protein 419 isoform 2

      See identical proteins and their annotated locations for NP_001020848.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      Q4V8J3
      Related
      ENSRNOP00000031196.3, ENSRNOT00000030259.5
      Conserved Domains (3) summary
      COG5048
      Location:51 → 204
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:55 → 75
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:67 → 92
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001399374.1 → NP_001386303.1  zinc finger protein 419 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A0G2KAA5
      Related
      ENSRNOP00000075325.2, ENSRNOT00000079497.3
      Conserved Domains (4) summary
      COG5048
      Location:192 → 345
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:196 → 216
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:41 → 82
      KRAB; KRAB box
      pfam13465
      Location:349 → 373
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      75735754..75742480 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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