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    Zfp954 zinc finger protein 954 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308320, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp954provided by RGD
    Official Full Name
    zinc finger protein 954provided by RGD
    Primary source
    RGD:1561308
    See related
    EnsemblRapid:ENSRNOG00000022742 AllianceGenome:RGD:1561308
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Zfp772
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF419 (zinc finger protein 419). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 76.7), Lung (RPKM 69.1) and 9 other tissues See more
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    Genomic context

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    See Zfp954 in Genome Data Viewer
    Location:
    1q12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (75809401..75815348)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (66776279..66782224)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (69853553..69859391)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene hippocampus abundant gene transcript 1, pseudogene 1 Neighboring gene zinc finger protein 773, pseudogene 1 Neighboring gene uncharacterized LOC108349540 Neighboring gene large ribosomal subunit protein uL23-like Neighboring gene zinc finger protein 773 Neighboring gene zinc finger protein 805 like, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 419
    Names
    zinc finger protein 772

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107472.1 → NP_001100942.1  zinc finger protein 419

      See identical proteins and their annotated locations for NP_001100942.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474102
      UniProtKB/TrEMBL
      A6KS55, D4A7C1
      Related
      ENSRNOP00000047509.3, ENSRNOT00000042086.6
      Conserved Domains (6) summary
      smart00349
      Location:42 → 95
      KRAB; krueppel associated box
      sd00017
      Location:199 → 219
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:363 → 385
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:42 → 81
      KRAB; KRAB box
      pfam13465
      Location:240 → 264
      zf-H2C2_2; Zinc-finger double domain
      pfam15909
      Location:336 → 409
      zf-C2H2_8; C2H2-type zinc ribbon

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      75809401..75815348
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063288674.1 → XP_063144744.1  zinc finger protein 419 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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