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    Entrep3 endosomal transmembrane epsin interactor 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310640, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Entrep3provided by RGD
    Official Full Name
    endosomal transmembrane epsin interactor 3provided by RGD
    Primary source
    RGD:1306107
    See related
    EnsemblRapid:ENSRNOG00000020518 AllianceGenome:RGD:1306107
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam189b; RGD1306107
    Summary
    Predicted to enable WW domain binding activity. Predicted to be located in membrane. Orthologous to human ENTREP3 (endosomal transmembrane epsin interactor 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 54.7), Spleen (RPKM 23.4) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Entrep3 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (176886903..176893047)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (174588984..174595281)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (188495237..188501444)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene CDC-like kinase 2 Neighboring gene microRNA 3541 Neighboring gene secretory carrier membrane protein 3 Neighboring gene uncharacterized LOC102550011 Neighboring gene glucosylceramidase beta 1 Neighboring gene transfer RNA valine (anticodon AAC) 42

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins. Ludes-Meyers JH, et al. Oncogene, 2004 Jun 24. PMID 15064722, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables WW domain binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein ENTREP3
    Names
    family with sequence similarity 189, member B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107690.1 → NP_001101160.1  protein ENTREP3

      See identical proteins and their annotated locations for NP_001101160.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473976
      UniProtKB/TrEMBL
      A0A8I6ABH6, A6J6C5
      Conserved Domains (1) summary
      pfam04103
      Location:36 → 196
      CD20; CD20-like family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      176886903..176893047
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039102316.2 → XP_038958244.1  protein ENTREP3 isoform X1

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:409 → 637
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36 → 200
      CD20; CD20-like family

    2. XM_039102317.2 → XP_038958245.1  protein ENTREP3 isoform X2

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:409 → 636
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36 → 200
      CD20; CD20-like family

    3. XM_039102322.2 → XP_038958250.1  protein ENTREP3 isoform X6

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:407 → 625
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36 → 200
      CD20; CD20-like family

    4. XM_039102323.2 → XP_038958251.1  protein ENTREP3 isoform X7

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:395 → 623
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36 → 200
      CD20; CD20-like family

    5. XM_008761169.4 → XP_008759391.1  protein ENTREP3 isoform X8

      UniProtKB/TrEMBL
      A0A8I6ABH6, D3Z8J6
      Conserved Domains (1) summary
      pfam04103
      Location:36 → 200
      CD20; CD20-like family

    6. XM_063281847.1 → XP_063137917.1  protein ENTREP3 isoform X16

      UniProtKB/TrEMBL
      A0A8I6ABH6

    7. XM_039102318.2 → XP_038958246.1  protein ENTREP3 isoform X3

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:408 → 636
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36 → 200
      CD20; CD20-like family

    8. XM_039102324.2 → XP_038958252.1  protein ENTREP3 isoform X9

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:394 → 622
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36 → 200
      CD20; CD20-like family

    9. XM_017590886.3 → XP_017446375.1  protein ENTREP3 isoform X10

      UniProtKB/TrEMBL
      A0A8I6ABH6

    10. XM_063281848.1 → XP_063137918.1  protein ENTREP3 isoform X17

      UniProtKB/TrEMBL
      A0A8I6ABH6

    11. XM_039102319.2 → XP_038958247.1  protein ENTREP3 isoform X4

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:405 → 633
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36 → 196
      CD20; CD20-like family

    12. XM_063281845.1 → XP_063137915.1  protein ENTREP3 isoform X12

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Related
      ENSRNOP00000027828.8, ENSRNOT00000027828.9

    13. XM_006232664.4 → XP_006232726.1  protein ENTREP3 isoform X11

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (1) summary
      pfam04103
      Location:36 → 196
      CD20; CD20-like family

    14. XM_063281849.1 → XP_063137919.1  protein ENTREP3 isoform X18

      UniProtKB/TrEMBL
      A0A8I6ABH6

    15. XM_039102320.2 → XP_038958248.1  protein ENTREP3 isoform X5

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:404 → 632
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36 → 196
      CD20; CD20-like family

    16. XM_063281846.1 → XP_063137916.1  protein ENTREP3 isoform X14

      UniProtKB/TrEMBL
      A0A8I6ABH6

    17. XM_063281851.1 → XP_063137921.1  protein ENTREP3 isoform X19

      UniProtKB/TrEMBL
      A0A8I6ABH6

    18. XM_039102328.2 → XP_038958256.1  protein ENTREP3 isoform X23

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:365 → 593
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36 → 156
      CD20; CD20-like family

    19. XM_063281855.1 → XP_063137925.1  protein ENTREP3 isoform X26

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Related
      ENSRNOP00000104427.1, ENSRNOT00000166647.1

    20. XM_063281856.1 → XP_063137926.1  protein ENTREP3 isoform X28

      UniProtKB/TrEMBL
      A0A8I6ABH6

    21. XM_039102329.2 → XP_038958257.1  protein ENTREP3 isoform X24

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:364 → 592
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36 → 156
      CD20; CD20-like family

    22. XM_039102325.2 → XP_038958253.1  protein ENTREP3 isoform X13

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:390 → 618
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36 → 181
      CD20; CD20-like family

    23. XM_039102326.2 → XP_038958254.1  protein ENTREP3 isoform X15

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:386 → 614
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36 → 177
      CD20; CD20-like family

    24. XM_063281852.1 → XP_063137922.1  protein ENTREP3 isoform X20

      UniProtKB/TrEMBL
      A0A8I6ABH6

    25. XM_039102327.2 → XP_038958255.1  protein ENTREP3 isoform X21

      UniProtKB/TrEMBL
      A0A8I6ABH6, A0A8I6GFC2
      Related
      ENSRNOP00000086795.2, ENSRNOT00000110005.2
      Conserved Domains (2) summary
      PHA03247
      Location:372 → 599
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36 → 177
      CD20; CD20-like family

    26. XM_063281853.1 → XP_063137923.1  protein ENTREP3 isoform X22

      UniProtKB/TrEMBL
      A0A8I6ABH6

    27. XM_063281854.1 → XP_063137924.1  protein ENTREP3 isoform X25

      UniProtKB/TrEMBL
      A0A8I6ABH6

    28. XM_039102330.2 → XP_038958258.1  protein ENTREP3 isoform X27

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:346 → 574
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36 → 137
      CD20; CD20-like family

    29. XM_063281857.1 → XP_063137927.1  protein ENTREP3 isoform X29

      UniProtKB/TrEMBL
      A0A8I6ABH6

    30. XM_063281858.1 → XP_063137928.1  protein ENTREP3 isoform X30

      UniProtKB/TrEMBL
      A0A8I6ABH6

    31. XM_039102332.2 → XP_038958260.1  protein ENTREP3 isoform X31

      Conserved Domains (1) summary
      PRK12323
      Location:231 → 446
      PRK12323; DNA polymerase III subunit gamma/tau

    32. XM_063281859.1 → XP_063137929.1  protein ENTREP3 isoform X31

    33. XM_063281861.1 → XP_063137931.1  protein ENTREP3 isoform X33

    34. XM_063281862.1 → XP_063137932.1  protein ENTREP3 isoform X34

    35. XM_063281860.1 → XP_063137930.1  protein ENTREP3 isoform X32

    Nucleotide Protein Strain
    Heading Accession and Version

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