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    Tm4sf5 transmembrane 4 L six family member 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303256, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tm4sf5provided by RGD
    Official Full Name
    transmembrane 4 L six family member 5provided by RGD
    Primary source
    RGD:1308709
    See related
    AllianceGenome:RGD:1308709
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable arginine binding activity. Predicted to be involved in regulation of G1/S transition of mitotic cell cycle. Predicted to be located in lysosomal membrane and plasma membrane. Predicted to be active in membrane. Orthologous to human TM4SF5 (transmembrane 4 L six family member 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 1.4), Testes (RPKM 0.2) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Tm4sf5 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (55718014..55724372)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (55219384..55225742)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (57111907..57118299)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 11 Neighboring gene C-X-C motif chemokine ligand 16 Neighboring gene zinc finger, MYND-type containing 15 Neighboring gene vitelline membrane outer layer 1 homolog Neighboring gene glycolipid transfer protein domain containing 2 Neighboring gene proteasome 20S subunit beta 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables arginine binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of G1/S transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    transmembrane 4 L6 family member 5
    Names
    transmembrane 4 superfamily member 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107015.1NP_001100485.1  transmembrane 4 L6 family member 5

      See identical proteins and their annotated locations for NP_001100485.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473948
      UniProtKB/TrEMBL
      A6HG57, D4ABR9
      Conserved Domains (1) summary
      pfam05805
      Location:1189
      L6_membrane; L6 membrane protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      55718014..55724372
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)